Trial reportArchives of women's mental health2016
PREPP: postpartum depression prevention through the mother-infant dyad.
Trial report in Archives of women's mental health, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
35 citing papers in PubMed, 5 syntheses or guidelines pooled it, 72 citations in OpenAlex.
- Maternal Mental Health and Offspring Brain Development: An Umbrella Review of Prenatal Interventions.Biological psychiatry · 2023Pooled it
- Interventions from pregnancy to two years after birth for parents experiencing complex post-traumatic stress disorder and/or with childhood experience of maltreatment.The Cochrane database of systematic reviews · 2023Pooled it
- Effect of Parenting Interventions on Perinatal Depression and Implications for Infant Developmental Outcomes: A Systematic Review and Meta-Analysis.Clinical child and family psychology review · 2022Pooled it
- Assessment and support during early labour for improving birth outcomes.The Cochrane database of systematic reviews · 2017Pooled it
- Can psychological interventions prevent or reduce risk for perinatal anxiety disorders? A systematic review and meta-analysis.General hospital psychiatryPooled it
- Practical resources for effective postpartum parenting (PREPP): a randomized controlled trial of a novel parent-infant dyadic intervention to reduce symptoms of postpartum depression.American journal of obstetrics & gynecology MFM · 2024Trial
- A randomised controlled trial evaluating the effect of a brief motivational intervention to promote breastfeeding in postpartum depression.Scientific reports · 2022Trial
- Preventing maternal mental health disorders in the context of poverty: pilot efficacy of a dyadic intervention.American journal of obstetrics & gynecology MFM · 2020Trial
- Labour and delivery characteristics, maternal birth satisfaction and early relational health among COVID-19 pandemic-born children.Journal of reproductive and infant psychology · 2026Article
- Alcohol consumption, mental health, and the moderating role of social isolation during the COVID-19 pandemic in southern Brazil.Revista brasileira de epidemiologia = Brazilian journal of epidemiology · 2026Article
- Report: Workshop on maternal mental health, February 11-12, 2024, cosponsored by the American College of Obstetricians and Gynecologists.Pregnancy (Hoboken, N.J.) · 2025Article
- Clinical Utility of Zuranolone for Postpartum Depression: A Narrative Review.Neuropsychiatric disease and treatment · 2025Review
- The Impact of Postpartum Depression on the Early Mother-Infant Relationship during the COVID-19 Pandemic: Perception versus Reality.International journal of environmental research and public health · 2024Article
- Review
- Examining Processes of Care Redesign: Direct Observation of Group Well-Child Care.Clinical pediatrics · 2023Article
- The effect of perinatal interventions on parent anxiety, infant socio-emotional development and parent-infant relationship outcomes: A systematic review.JCPP advances · 2022Article
- The transition to parenthood in obstetrics: enhancing prenatal care for 2-generation impact.American journal of obstetrics & gynecology MFM · 2022Review
- Estimation of postpartum depression risk from electronic health records using machine learning.BMC pregnancy and childbirth · 2021Article
- Maternal-fetal attachment in pregnant Italian women: multidimensional influences and the association with maternal caregiving in the infant's first year of life.BMC pregnancy and childbirth · 2021Article
- Perinatal depression prevention through the mother-infant dyad: The role of maternal childhood maltreatment.Journal of affective disorders · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
Most interventions to prevent postpartum depression (PPD) focus on the mother rather than the mother-infant dyad. As strong relationships between infant sleep and cry behavior and maternal postpartum mood have been demonstrated by previous research, interventions targeted at the dyad may reduce symptoms of PPD. The goal of the current study was to examine the effectiveness of Practical Resources for Effective Postpartum Parenting (PREPP). PREPP is a new PPD prevention protocol that aims to treat women at risk for PPD by promoting maternally mediated behavioral changes in their infants, while also including mother-focused skills. Results of this randomized control trial (RCT) (n = 54) indicate that this novel, brief intervention was well tolerated and effective in reducing maternal symptoms of anxiety and depression, particularly at 6 weeks postpartum. Additionally, this study found that infants of mothers enrolled in PREPP had fewer bouts of fussing and crying at 6 weeks postpartum than those infants whose mothers were in the Enhanced TAU group. These preliminary results indicate that PREPP has the potential to reduce the incidence of PPD in women at risk and to directly impact the developing mother-child relationship, the mother's view of her child, and child outcomes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.