Evidence map›Paper›PMID 26231253›Full record

ArticleLa Radiologia medica2016

CT patterns of pleuro-pulmonary damage caused by inhalation of pumice as a model of pneumoconiosis from non-fibrous amorphous silicates.

Chiara Costa, Giorgio Ascenti, Emanuele Scribano, Tommaso D'Angelo, Michele Gaeta, Concettina Fenga, Alfredo Blandino, Silvio Mazziotti

Abstract read
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In one paragraph

Article in La Radiologia medica, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Chiara CostaDepartment of Environment, Security, Territory, Food and Health Sciences-Occupational Medicine Section, Policlinico "G. Martino", University of Messina, Via Consolare Valeria 1, 98125, Messina, Italy.
Giorgio AscentiDepartment of Biomedical Sciences and Morphological and Functional Imaging, Policlinico "G. Martino", University of Messina, Via Consolare Valeria 1, 98100, Messina, Italy.
Emanuele ScribanoDepartment of Biomedical Sciences and Morphological and Functional Imaging, Policlinico "G. Martino", University of Messina, Via Consolare Valeria 1, 98100, Messina, Italy.
Tommaso D'AngeloDepartment of Biomedical Sciences and Morphological and Functional Imaging, Policlinico "G. Martino", University of Messina, Via Consolare Valeria 1, 98100, Messina, Italy. tommasodang@gmail.com.ORCID http://orcid.org/0000-0003-0004-6378
Michele GaetaDepartment of Biomedical Sciences and Morphological and Functional Imaging, Policlinico "G. Martino", University of Messina, Via Consolare Valeria 1, 98100, Messina, Italy.
Concettina FengaDepartment of Environment, Security, Territory, Food and Health Sciences-Occupational Medicine Section, Policlinico "G. Martino", University of Messina, Via Consolare Valeria 1, 98125, Messina, Italy.
Alfredo BlandinoDepartment of Biomedical Sciences and Morphological and Functional Imaging, Policlinico "G. Martino", University of Messina, Via Consolare Valeria 1, 98100, Messina, Italy.
Silvio MazziottiDepartment of Biomedical Sciences and Morphological and Functional Imaging, Policlinico "G. Martino", University of Messina, Via Consolare Valeria 1, 98100, Messina, Italy.
University of Messina · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe aim of this article is to correlate the radiological features of pleuro-pulmonary damage caused by inhalation of pumice (an extrusive volcanic rock classified as a non-fibrous, amorphous, complex silicate) with exposure conditions. MATERIALS AND

methods36 subjects employed in the pumice quarries were evaluated for annual follow-up in a preventive medical surveillance program including spirometry, chest CT lasting from 1999 to 2014. They were only male subjects, mean age 56.92 ± 16.45 years. Subjects had worked in the quarries for an average of 25.03 ± 9.39 years. Domestic or occupational exposure to asbestos or other mineral dusts other than pumice was excluded. Subjects were also classified as smokers, former smokers and nonsmokers.

resultsAmong the 36 workers examined, we identified four CT patterns which resulted to be dependent on exposure duration and intensity, FVC, FEV1 and FEF25-75, but not on cigarette smoking. The most common symptoms reported by clinical examination were dyspnoea, cough and asthenia. In no case it was proven an evolution of CT findings during follow-up for 10 years.

conclusionsLiparitosis, caused by pumice inhalation, can be considered a representative example of pneumoconiosis derived by amorphous silica compounds, which are extremely widespread for industrial manufacturing as well as for applicative uses, such as nano-materials. Moreover, being pumice free of quartz contamination, it can represent a disease model for exposure to pure non-fibrous silicates.

Indexed as

AdultAgedDustHumansInhalation ExposureItalyMaleMicroscopy, Electron, ScanningMiddle AgedOccupational ExposurePneumoconiosisRespiratory Function TestsSilicatesTomography, X-Ray ComputedDustpumiceSilicatesAmorphous silicaComputed tomographyLungPleuraPneumoconiosisPumice

Identifiers

PMID26231253
OpenAlexW1090669939

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.