Evidence map›Paper›PMID 26231181›Full record

Observational studyBMC endocrine disorders2015

Effects of an eight-week supervised, structured lifestyle modification programme on anthropometric, metabolic and cardiovascular risk factors in severely obese adults.

Catherine Crowe, Irene Gibson, Katie Cunningham, Claire Kerins, Caroline Costello, Jane Windle, Paula M O Shea, Mary Hynes, Brian McGuire, Katriona Kilkelly and 4 more

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in BMC endocrine disorders, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 1 country.

Catherine CroweBariatric Medicine Service, Galway Diabetes Research Centre, HRB Clinical Research Facility, Galway University Hospital, Galway, Ireland.
Irene GibsonCroi, the West of Ireland Cardiac Foundation, Heart and Stroke Centre, Moyola Lane, Newcastle, Galway, Ireland.
Katie CunninghamBariatric Medicine Service, Galway Diabetes Research Centre, HRB Clinical Research Facility, Galway University Hospital, Galway, Ireland.
Claire KerinsCroi, the West of Ireland Cardiac Foundation, Heart and Stroke Centre, Moyola Lane, Newcastle, Galway, Ireland.
Caroline CostelloCroi, the West of Ireland Cardiac Foundation, Heart and Stroke Centre, Moyola Lane, Newcastle, Galway, Ireland.
Jane WindleCroi, the West of Ireland Cardiac Foundation, Heart and Stroke Centre, Moyola Lane, Newcastle, Galway, Ireland.
Paula M O SheaDepartment of Clinical Biochemistry, Galway University Hospitals, Galway, Ireland.
Mary HynesBariatric Medicine Service, Galway Diabetes Research Centre, HRB Clinical Research Facility, Galway University Hospital, Galway, Ireland.
Brian McGuireSchool of Psychology, National University of Ireland, Galway, Ireland.
Katriona KilkellyBariatric Medicine Service, Galway Diabetes Research Centre, HRB Clinical Research Facility, Galway University Hospital, Galway, Ireland.
Helena GriffinBariatric Medicine Service, Galway Diabetes Research Centre, HRB Clinical Research Facility, Galway University Hospital, Galway, Ireland.
Tim O BrienBariatric Medicine Service, Galway Diabetes Research Centre, HRB Clinical Research Facility, Galway University Hospital, Galway, Ireland.
Jenni JonesDiscipline of Health Promotion, National University of Ireland, Galway, Ireland.
Francis M FinucaneBariatric Medicine Service, Galway Diabetes Research Centre, HRB Clinical Research Facility, Galway University Hospital, Galway, Ireland. francis.finucane@hse.ie.
Ollscoil na Gaillimhe – University of Galway · IEUniversity Hospital Galway · IECroí · IE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLifestyle modification is fundamental to obesity treatment, but few studies have described the effects of structured lifestyle programmes specifically in bariatric patients. We sought to describe changes in anthropometric and metabolic characteristics in a cohort of bariatric patients after participation in a nurse-led, structured lifestyle programme.

methodsWe conducted a retrospective, observational cohort study of adults with a body mass index (BMI) ≥ 40 kgm(-2) (or ≥ 35 kgm(-2) with significant co-morbidity) who were attending a regional bariatric service and who completed a single centre, 8-week, nurse-led multidisciplinary lifestyle modification programme. Weight, height, waist circumference, blood pressure, HbA1c, fasting glucose and lipid profiles as well as functional capacity (Incremental Shuttle Walk Test) and questionnaire-based anxiety and depression scores before and after the programme were compared in per-protocol analyses.

resultsOf 183 bariatric patients enrolled, 150 (81.9%) completed the programme. Mean age of completers was 47.9 ± 1.2 years. 34.7% were male. There were statistically significant reductions in weight (129.6 ± 25.9 v 126.9 ± 26.1 kg, p < 0.001), BMI (46.3 ± 8.3 v 44.9 ± 9.0 kgm(-2), p < 0.001), waist circumference (133.0 ± 17.1 v 129.3 ± 17.5 cm in women and 143.8 ± 19.0 v 135.1 ± 17.9 cm in men, both p < 0.001) as well as anxiety and depression scores, total- and LDL-cholesterol and triglyceride levels, with an increase in functional capacity (5.9 ± 1.7 v 6.8 ± 2.1 metabolic equivalents of thermogenesis (METS), p < 0.001) in completers at the end of the programme compared to the start. Blood pressure improved, with reductions in systolic and diastolic blood pressure from 135 ± 16.2 to 131.6 ± 17.1 (p = 0.009) and 84.7 ± 10.2 to 81.4 ± 10.9 mmHg (p < 0.001), respectively. The proportion of patients achieving target blood pressure increased from 50.3 to 59.3% (p = 0.04). The proportion of patients with diabetes achieving HbA1c <53 mmol/mol increased from 28.6 to 42.9%, p = 0.02.

conclusionsBariatric patients completing an 8 week, nurse-led structured lifestyle programme had improved adiposity, fitness, lipid profiles, psychosocial health, blood pressure and glycaemia. Further assessment of this programme in a pragmatic randomised controlled trial seems warranted.

Indexed as

Diet TherapyExercise TherapyAdultAnxietyBlood GlucoseBody HeightBody WeightCardiovascular DiseasesCholesterol, HDLCholesterol, LDLCohort StudiesDepressionDiabetes Mellitus, Type 2Exercise TestExercise ToleranceFemaleBlood GlucoseCholesterol, HDLCholesterol, LDLGlycated Hemoglobinhemoglobin A1c protein, humanTriglycerides

Identifiers

PMID26231181
PMCPMC4522055
OpenAlexW1876886491

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.