Trial reportInternational journal of geriatric psychiatry2016
The impact of executive function on response to cognitive behavioral therapy in late-life depression.
Trial report in International journal of geriatric psychiatry, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 50 citations in OpenAlex.
- Recent Advances in Psychological Interventions Targeting Cognitive Dysfunction in Adults with Major Depressive Disorder: A Systematic Review.Advances in experimental medicine and biology · 2026Pooled it
- Objectively measured cognitive function in insomnia patients with and without comorbid depression treated with cognitive behavioral therapy for insomnia.BMC psychiatry · 2025Trial
- Therapeutic relationship in the treatment of geriatric depression with executive dysfunction.Journal of affective disorders · 2017Trial
- Relation Between Executive Function Test Performance and Treatment Outcomes During Brief Psychotherapies for Later-Life Depression.The American journal of geriatric psychiatry. Open science, education, and practice · 2025Article
- Transdiagnostic Attentional Deficits Are Associated with Depressive and Externalizing Symptoms in Children and Adolescents with Neuropsychiatric Disorders.Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists · 2025Article
- Chronic exercise interventions for executive function in overweight children: a systematic review and meta-analysis.Frontiers in sports and active living · 2024Review
- The Role of Emotion Regulation and Executive Functioning in the Intervention Outcome of Children with Emotional and Behavioural Problems.Children (Basel, Switzerland) · 2023Article
- Neuroscience-based psychotherapy: A position paper.Frontiers in psychology · 2023Article
- Executive functioning as a predictor of response to interpersonal psychotherapy in adolescents with depression: A pilot study.Journal of affective disorders reports · 2022Article
- Executive Functions of Adults with Binge-Eating Disorder: The Role of Weight Status and Psychopathology.Brain sciences · 2021Article
- Lifetime Trauma History and Cognitive Functioning in Major Depression and Their Role for Cognitive-Behavioral Therapy Outcome.Clinical psychology in Europe · 2021Article
- Comparing objective cognitive impairments in patients with peripheral neuropathic pain or fibromyalgia.Scientific reports · 2021Article
- Neurocognitive predictors of treatment completion and daytime activities at follow-up in multiproblem young adults.Cognitive, affective & behavioral neuroscience · 2020Article
- Psychosocial Treatment Options for Major Depressive Disorder in Older Adults.Current treatment options in psychiatry · 2017Article
Corrections and comments
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Authors and funding
9 authors at 5 institutions in 1 country.
Funding
Abstract
objectiveLate-life depression (LLD) is a common and debilitating condition among older adults. Cognitive behavioral therapy (CBT) has strong empirical support for the treatment of depression in all ages, including in LLD. In teaching patients to identify, monitor, and challenge negative patterns in their thinking, CBT for LLD relies heavily on cognitive processes and, in particular, executive functioning, such as planning, sequencing, organizing, and selectively inhibiting information. It may be that the effectiveness of CBT lies in its ability to train these cognitive areas.
methodsParticipants with LLD completed a comprehensive neuropsychological battery before enrolling in CBT. The current study examined the relationship between neuropsychological function prior to treatment and response to CBT.
resultsWhen using three baseline measures of executive functioning that quantify set shifting, cognitive flexibility, and response inhibition to predict treatment response, only baseline Wisconsin Card Sort Task performance was associated with a significant drop in depression symptoms after CBT. Specifically, worse performance on the Wisconsin Card Sort Task was associated with better treatment response.
conclusionsThese results suggest that CBT, which teaches cognitive techniques for improving psychiatric symptoms, may be especially beneficial in LLD if relative weaknesses in specific areas of executive functioning are present.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.