Evidence map›Paper›PMID 26229954›Full record

ArticleBioMed research international2015

Results from the Registry of Atrial Fibrillation (AFABE): Gap between Undiagnosed and Registered Atrial Fibrillation in Adults--Ineffectiveness of Oral Anticoagulation Treatment with VKA.

Anna Panisello-Tafalla, Josep Lluís Clua-Espuny, Vicente F Gil-Guillen, Antonia González-Henares, María Lluisa Queralt-Tomas, Carlos López-Pablo, Jorgina Lucas-Noll, Iñigo Lechuga-Duran, Rosa Ripolles-Vicente, Jesús Carot-Domenech and 1 more

Registry-linked trialOpen access · hybridAbstract readMulticenter Study
In one paragraph

Article in BioMed research international, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03589170 (Atrial Fibrilation Opportunistic Screening and Stroke Incidence), which is not on this map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03589170 unknown statusnot on this mapstarted 2016, after this paper: background citation

Atrial Fibrilation Opportunistic Screening and Stroke Incidence (AFOSS): Searching the Unknown Atrial Fibrillation.

Typeobservational_patient_registrySponsorFundacio d'Investigacio en Atencio Primaria Jordi Gol i GurinaRan2016 to 2019Enrolled51,410ConditionsAtrial FibrillationArmsOpportunistic atrial fibrillation screening
3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Impact of atrial fibrillation on pulmonary embolism hospitalization: Nationwide analysis.American heart journal plus : cardiology research and practice · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Anna Panisello-TafallaEAP Tortosa 1-Oest, Institut Català Salut, SAP Terres de l'Ebre, Health Department, Generalitat de Catalunya, CAP Roquetes, 43520 Tortosa, Spain.
Josep Lluís Clua-EspunyEAP Tortosa 1-Est, Institut Català Salut, SAP Terres de l'Ebre, Health Department, Generalitat de Catalunya, CAP Temple, 43500 Tortosa, Spain ; Miguel Hernández University, 03202 Elche, Spain.
Vicente F Gil-GuillenMiguel Hernández University, 03202 Elche, Spain.
Antonia González-HenaresEAP-Camarles-Aldea-Ampolla, Institut Català Salut, SAP Terres de l'Ebre, Health Department, Generalitat de Catalunya, CAP Ampolla, 43895 Tortosa, Spain.
María Lluisa Queralt-TomasEAP Tortosa-2-Oest, Institut Català Salut, SAP Terres de l'Ebre, Health Department, Generalitat de Catalunya, CAP Xerta, 43592 Tortosa, Spain.
Carlos López-PabloMolecular Biology and Research Section, Hospital de Tortosa Verge de la Cinta, IISPV, IDIAP, 43500 Tortosa, Spain.
Jorgina Lucas-NollEAP Deltebre, Institut Català Salut, SAP Terres de l'Ebre, Health Department, Generalitat de Catalunya, CAP Deltebre, 43580 Tortosa, Spain.
Iñigo Lechuga-DuranDepartment of Cardiology, Hospital de Tortosa Verge de la Cinta, IISPV, 43500 Tortosa, Spain.
Rosa Ripolles-VicenteEAP Tortosa 1-Est, Institut Català Salut, SAP Terres de l'Ebre, Health Department, Generalitat de Catalunya, CAP Temple, 43500 Tortosa, Spain.
Jesús Carot-DomenechDepartment of Systems Management, Hospital de Tortosa Verge de la Cinta, Institut Català de la Salut, 43500 Tortosa, Spain.
Miquel Gallofré LópezPla Director de la Malaltia Vascular Cerebral de Catalunya, Department Salut de la Generalitat de Catalunya, 08005 Barcelona, Spain.
Government of Catalonia · ESHospital de Tortosa Virgen de la Cinta · ESUniversitat de Miguel Hernández d'Elx · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study aimed to examine the effectiveness of the use of oral anticoagulation (OAC) medication, recommended by national guidelines for stroke prevention but reportedly underused in AF patients with moderate to high stroke risk.

methodA multicentre and cross-sectional study of undiagnosed AF among out-of-hospital patients over 60 years old was carried out, visiting 3,638 patients at primary health centres or at home for AF diagnosis using the IDC-10 classification. The main outcome measures were CHA₂DS₂VASC, HAS-BLED scores, cardiovascular comorbidity, pharmacological information, TTR, and SAMe-TT2R2 scores.

resultsThe main findings were undiagnosed AF in 26.44% of cases; 31.04% registered with AF but not using OAC despite 95.6% having a CHA₂DS₂VASC ≥ 2 score; a risk of bleeding in important subgroups using OAC without indication (37.50% CHA₂DS₂VASC < 2 score); the use of OAC with TTR < 60% (33.1%), of whom 47.6% had a HAS-BLED score ≥3. Thus, 35.4% of the expected AF prevalence achieved an optimal time in the therapeutic range.

conclusionsThe expected AF prevalence was 10.9% (n 5267), but the registered prevalence was 7.5% (n 3638). Only 35.04% (CI = 95%, 33.7-36.3) of AF patients treated with vitamin K antagonists (VKAs) achieve the goal of TTR > 60%.

Indexed as

RegistriesAdministration, OralAdultAgedAnticoagulantsAtrial FibrillationFemaleHumansMalePrevalenceRisk FactorsSpainSurvival AnalysisVitamin KAnticoagulantsVitamin K

Identifiers

PMID26229954
PMCPMC4502299
OpenAlexW1912202071

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.