ArticleAvicenna journal of medicine
Visceral adipose tissue influences on coronary artery calcification at young and middle-age groups using computed tomography angiography.
Article in Avicenna journal of medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Gender differences in patients presenting with premature coronary artery disease.Journal of family medicine and primary care · 2025Article
- Identifying risk factors and mortality rate of premature coronary artery disease in young Saudi population.Scientific reports · 2024Article
- Association of Anthropometric and CT-Based Obesity Indices with Subclinical Atherosclerosis.Journal of atherosclerosis and thrombosis · 2024Article
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Authors and funding
6 authors.
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Abstract
purposeThe purpose of the study was to evaluate the impact of excessive visceral adipose tissue (VAT) on subclinical coronary atherosclerosis and coronary artery calcifications (CAC) in young and middle-age groups using multislice computed tomography.
methodsThis study is a single center, cross-sectional study. Eligible patients (n = 159), who under the age of 61 years, with chest pain and mild to moderate probability to have coronary artery disease (CAD) were enrolled. Coronary calcium score and epicardial adipose tissue (EAT) were measured at the level of the left main coronary artery while VAT was measured at the level of the iliac crest.
resultsThe average age was (48 ± 8 years). The mean VAT was (38 ± 21 cm(2)) with no significant difference between men and women (38 ± 22 vs. 37 ± 19 P = 0.8) respectively. Student's t-test analysis showed significantly higher VAT in patients with detectable CAC than patients with no CAC (48 ± 24 vs. 33 ± 18 P = 0.00002), respectively. Univariate regression analysis showed that VAT and EAT, are strong predictor for CAC (hazard ratio [HR] 1.034, 95% confidence interval [CI: 1.016-1.052]. P <0.001 and [HR] 1.344, 95% CI: [1.129-1.601] P = 0.001), respectively.
conclusionExcessive VAT is significantly associated with positive CAC. VAT can strongly predict subclinical CAD in individuals at young and middle-age groups.
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