ArticleRSC advances
The Role of Hydroxyl Channel in Defining Selected Physicochemical Peculiarities Exhibited by Hydroxyapatite.
Article in RSC advances. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
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Who cites it
34 citing papers in PubMed.
- Metal Ions in Longgu (Fossilized Bone) as a Natural Synergistic Network for Multi-Target Therapy in Psychiatric Disorders.Chemistry & biodiversity · 2026Review
- Defect-Related Photoluminescence in Hydroxyapatite Nanoparticles Modulated by Carbonate Incorporation.ACS nanoscience Au · 2026Article
- Hexagonal-to-Monoclinic Phase-Modulated HAp Nanofibers for Enhanced Piezoelectric and Biocompatible Performance.Biomolecules · 2026Article
- Osteoblast and osteoclast responses to chelate-setting calcium phosphate cements with different solubilities.Biomaterials and biosystems · 2026Article
- Nanostructured Sr-Doped Hydroxyapatite: A Material with Antimicrobial Potential.Nanomaterials (Basel, Switzerland) · 2025Article
- Hybrid Hydroxyapatite-Metal Complex Materials Derived from Amino Acids and Nucleobases.Molecules (Basel, Switzerland) · 2024Review
- The Conundrum of "Pair Sites" in Langmuir-Hinshelwood Reaction Kinetics in Heterogeneous Catalysis.ACS catalysis · 2024Review
- Correlation between positron annihilation lifetime and photoluminescence measurements for calcined Hydroxyapatite.Scientific reports · 2024Article
- Formation of Hydroxyapatite-Based Hybrid Materials in the Presence of Platelet-Poor Plasma Additive.Biomimetics (Basel, Switzerland) · 2023Article
- Polyvinylpyrrolidone-Alginate-Carbonate Hydroxyapatite Porous Composites for Dental Applications.Materials (Basel, Switzerland) · 2023Article
- Strontium Substituted β-Tricalcium Phosphate Ceramics: Physiochemical Properties and Cytocompatibility.Molecules (Basel, Switzerland) · 2022Article
- Design Strategies and Biomimetic Approaches for Calcium Phosphate Scaffolds in Bone Tissue Regeneration.Biomimetics (Basel, Switzerland) · 2022Review
- Nanomedicine for the poor: a lost cause or an idea whose time has yet to come?Nanomedicine (London, England) · 2021Article
- Empirical and theoretical insights into the structural effects of selenite doping in hydroxyapatite and the ensuing inhibition of osteoclasts.Materials science & engineering. C, Materials for biological applications · 2020Article
- Calcium and hydroxyapatite binding site of human vitronectin provides insights to abnormal deposit formation.Proceedings of the National Academy of Sciences of the United States of America · 2020Article
- Waiting for Aπαταω: 250 Years Later.Foundations of science · 2019Article
- Average and Local Structure of Apatite-Type Germanates and Implications for Oxide Ion Conductivity.Inorganic chemistry · 2019Article
- Mechanism of formation governs the mechanism of release of antibiotics from calcium phosphate nanopowders and cements in a drug-dependent manner.Journal of materials chemistry. B · 2019Article
- The solid-state proton NMR study of bone using a dipolar filter: apatite hydroxyl contentRSC advances · 2019Article
- Adsorptive Removal of Fluoride from Water Using Nanomaterials of Ferrihydrite, Apatite, and Brucite: Batch and Column Studies.Environmental engineering science · 2019Article
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Abstract
Mysteries surrounding the most important mineral for the vertebrate biology, hydroxyapatite, are many. Perhaps the Greek root of its name, απαταo, meaning 'to deceive' and given to its mineral form by the early gem collectors who confused it with more precious stones, is still applicable today, though in a different connotation, descriptive of a number of physicochemical peculiarities exhibited by it. Comparable to water as the epitome of peculiarities in the realm of liquids, hydroxyapatite can serve as a paradigm for peculiarities in the world of solids. Ten of the peculiar properties of hydroxyapatite are sketched in this review piece, ranging from (i) the crystal lattice flexibility to (ii) notorious surface layer instability to (iii) finite piezoelectricity, pyroelectricity and conductivity to protons to (iv) accelerated growth and improved osteoconductivity in the electromagnetic fields to (v) high nucleation rate at low supersaturations and low crystal growth rate at high supersaturations to (vi) higher bioactivity and resorbability of biological apatite compared to the synthetic ones, and beyond. An attempt has been made to explain this array of curious characteristics by referring to a particular element of the crystal structure of hydroxyapatite: the hydroxyl ion channel extending in the direction of the c-axis, through a crystallographic column created by the overlapping calcium ion triangles.
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