ArticleInternational journal of nanomedicine2015
Increased osteoblast function in vitro and in vivo through surface nanostructuring by ultrasonic shot peening.
Article in International journal of nanomedicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Article
- Biological Applications of Severely Plastically Deformed Nano-Grained Medical Devices: A Review.Nanomaterials (Basel, Switzerland) · 2021Review
- Mg-Phenolic Network Strategy for Enhancing Corrosion Resistance and Osteocompatibility of Degradable Magnesium Alloys.ACS omega · 2019Article
- Multiscale experimental study on the effects of different weight-bearing levels during moderate treadmill exercise on bone quality in growing female rats.Biomedical engineering online · 2019Article
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Authors and funding
7 authors.
Funding
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Abstract
Surface topography has significant influence on good and fast osseointegration of biomedical implants. In this work, ultrasonic shot peening was conducted to modify titanium to produce nanograined (NG) surface. Its ability to induce new bone formation was evaluated using an in vivo animal model. We demonstrated that the NG surface enhanced osteoblast adhesion, proliferation, differentiation, and mineralization in in vitro experiments compared to coarse-grained titanium surface. Push-out test, histological observations, fluorescent labeling, and histomorphometrical analysis consistently indicated that the NG surfaces developed have the higher osseointegration than coarse-grained surfaces. Those results suggest that ultrasonic shot peening has the potential for future use as a surface modification method in biomedical application.
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