ReviewWorld journal of gastroenterology2015
Gastroesophageal reflux and congenital gastrointestinal malformations.
Review in World journal of gastroenterology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Guidelines on diagnosis and management of gastroesophageal reflux disease in infants, children and adolescents: a joint consensus from Italian pediatric societies (SIP and SIGENP) -part I. diagnosis.Italian journal of pediatrics · 2026Guideline
- A clinical consensus guideline for nutrition in infants with congenital diaphragmatic hernia from birth through discharge.Journal of perinatology : official journal of the California Perinatal Association · 2024Guideline
- Acute appendicitis and situs viscerum inversus: radiological and surgical approach-a systematic review.European journal of medical research · 2023Pooled it
- Rectal Omeprazole in Infants With Gastroesophageal Reflux Disease: A Randomized Pilot Trial.European journal of drug metabolism and pharmacokinetics · 2020Trial
- Growth failure and early recurrence in congenital diaphragmatic hernia: An international cohort study.Journal of pediatric surgery · 2026Article
- Article
- Article
- Recent advances in machine learning for precision diagnosis and treatment of esophageal disorders.World journal of gastroenterology · 2025Review
- Childhood gastroesophageal reflux disease: A comprehensive review of disease, diagnosis, and therapeutic management.World journal of clinical pediatrics · 2025Review
- Oesophageal stricture in a cat with true pleuroperitoneal hernia.Veterinary medicine and science · 2024Article
- Long-term follow-up of patients with congenital diaphragmatic hernia.World journal of pediatric surgery · 2024Review
- Pathogenesis, diagnosis, dietary management, and prevention of gastrointestinal disorders in the paediatric population.Italian journal of pediatrics · 2022Review
- Congenital diaphragmatic hernia.Nature reviews. Disease primers · 2022Review
- Prioritization and functional analysis of GWAS risk loci for Barrett's esophagus and esophageal adenocarcinoma.Human molecular genetics · 2022Article
- Engineered Full Thickness Electrospun Scaffold for Esophageal Tissue Regeneration: From In Vitro to In Vivo Approach.Pharmaceutics · 2022Article
- Outcomes of sonographically-suspected fetal intra-abdominal cysts: Surgical intervention, conservative management and spontaneous regression.Frontiers in pediatrics · 2022Article
- Diagnostic accuracy of ultrasonography for the prenatal diagnosis of esophageal atresia and tracheoesophageal fistula.Experimental and therapeutic medicine · 2021Article
- Gastroesophageal Reflux Disease and Foregut Dysmotility in Children with Intestinal Failure.Nutrients · 2020Review
- Focus on gastroesophageal reflux disease in patients with cystic fibrosis.World journal of gastroenterology · 2020Review
- Development and Stability Study of an Omeprazole Suppository for Infants.European journal of drug metabolism and pharmacokinetics · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Although the outcome of newborns with surgical congenital diseases (e.g., diaphragmatic hernia; esophageal atresia; omphalocele; gastroschisis) has improved rapidly with recent advances in perinatal intensive care and surgery, infant survivors often require intensive treatment after birth, have prolonged hospitalizations, and, after discharge, may have long-term sequelae including gastro-intestinal comorbidities, above all, gastroesophageal reflux (GER). This condition involves the involuntary retrograde passage of gastric contents into the esophagus, with or without regurgitation or vomiting. It is a well-recognized condition, typical of infants, with an incidence of 85%, which usually resolves after physiological maturation of the lower esophageal sphincter and lengthening of the intra-abdominal esophagus, in the first few months after birth. Although the exact cause of abnormal esophageal function in congenital defects is not clearly understood, it has been hypothesized that common (increased intra-abdominal pressure after closure of the abdominal defect) and/or specific (e.g., motility disturbance of the upper gastrointestinal tract, damage of esophageal peristaltic pump) pathological mechanisms may play a role in the etiology of GER in patients with birth defects. Improvement of knowledge could positively impact the long-term prognosis of patients with surgical congenital diseases. The present manuscript provides a literature review focused on pathological and clinical characteristics of GER in patients who have undergone surgical treatment for congenital abdominal malformations.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.