Evidence map›Paper›PMID 26229221›Full record

ArticleDisease markers2015

Hemostatic Parameters according to Renal Function and Time after Transplantation in Brazilian Renal Transplanted Patients.

Ana Paula Lucas Mota, Patrícia Nessralla Alpoim, Roberta Carvalho de Figueiredo, Ana Cristina Simões e Silva, Karina Braga Gomes, Luci Maria SantAna Dusse

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Disease markers, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Ana Paula Lucas MotaDepartamento de Analises Clínicas e Toxicológicas, Faculdade de Farmácia, Universidade Federal de Minas Gerais, 31270901 Belo Horizonte, MG, Brazil.
Patrícia Nessralla AlpoimDepartamento de Analises Clínicas e Toxicológicas, Faculdade de Farmácia, Universidade Federal de Minas Gerais, 31270901 Belo Horizonte, MG, Brazil.
Roberta Carvalho de FigueiredoDepartamento de Ciências da Saúde, Faculdade de Farmácia, Universidade Federal de São João del-Rei, 35501296 Divinópolis, MG, Brazil.
Ana Cristina Simões e SilvaDepartamento de Pediatria, Faculdade de Medicina, Universidade Federal de Minas Gerais, 30130100 Belo Horizonte, MG, Brazil.
Karina Braga GomesDepartamento de Analises Clínicas e Toxicológicas, Faculdade de Farmácia, Universidade Federal de Minas Gerais, 31270901 Belo Horizonte, MG, Brazil.
Luci Maria SantAna DusseDepartamento de Analises Clínicas e Toxicológicas, Faculdade de Farmácia, Universidade Federal de Minas Gerais, 31270901 Belo Horizonte, MG, Brazil.
Universidade Federal de Minas Gerais · BRFederal University of São João del-Rei · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Kidney transplantation is the key for patients with end-stage renal disease, improving quality of life and longer survival. However, kidney transplant triggers an intense inflammatory response and alters the hemostatic system, but the pathophysiological mechanisms of these changes are not completely understood. The aim of this cross-sectional cohort study was to investigate hemostatic biomarkers in Brazilian renal transplanted patients according to renal function and time after transplantation. A total of 159 renal transplanted patients were enrolled and D-Dimer (D-Di), Thrombomodulin (TM), von Willebrand Factor (VWF), and ADAMTS13 plasma levels were assessed by ELISA. An increase of D-Di was observed in patients with higher levels of creatinine. ADAMTS13 levels were associated with creatinine plasma levels and D-Di levels with Glomerular Filtration Rate. These results suggested that D-Di and ADAMTS13 can be promising markers to estimate renal function. ADAMTS13 should be investigated throughout the posttransplant time to clarify the participation of this enzyme in glomerular filtration and acceptance or rejection of the graft in Brazilian transplanted patients.

Indexed as

HemostasisADAM ProteinsADAMTS13 ProteinAdolescentAdultAgedBiomarkersBrazilDelayed Graft FunctionFemaleFibrin Fibrinogen Degradation ProductsGraft RejectionHumansKidneyKidney TransplantationMaleADAM ProteinsADAMTS13 ProteinADAMTS13 protein, humanBiomarkersFibrin Fibrinogen Degradation Productsfibrin fragment DThrombomodulinvon Willebrand Factor

Identifiers

PMID26229221
PMCPMC4502328
OpenAlexW1601348583

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.