ArticleScientific reports2015
Chemical and Physical Characteristics of Doxorubicin Hydrochloride Drug-Doped Salmon DNA Thin Films.
Article in Scientific reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Anticancer effects of folic acid-functionalized covalent organic framework containing doxorubicin on SW480 colon cancer cells: a promising tool for drug targeted delivery.BMC biotechnology · 2025Article
- Dual-band transparency over near-IR and THz in surfactant-free DNA solid film.Scientific reports · 2024Article
- Article
- Nucleolin-Targeting AS1411 Aptamer-Conjugated Nanospheres for Targeted Treatment of Glioblastoma.Pharmaceutics · 2024Article
- Linear and nonlinear optical properties of transfer ribonucleic acid (tRNA) thin solid films.RSC advances · 2022Article
- Sequence Does Not Matter: The Biomedical Applications of DNA-Based Coatings and Cores.International journal of molecular sciences · 2021Review
- 3D-Printed Drug Capture Materials Based on Genomic DNA Coatings.ACS applied materials & interfaces · 2021Article
- Effect of TAT-DOX-PEG irradiated gold nanoparticles conjugates on human osteosarcoma cells.Scientific reports · 2020Article
- Large-Scale Fabrication of Copper-Ion-Coated Deoxyribonucleic Acid Hybrid Fibers by Ion Exchange and Self-Metallization.ACS omega · 2019Article
- Topological, chemical and electro-optical characteristics of riboflavin-doped artificial and natural DNA thin films.Royal Society open science · 2018Article
- Article
- Luminophore Configuration and Concentration-Dependent Optoelectronic Characteristics of a Quantum Dot-Embedded DNA Hybrid Thin film.Scientific reports · 2017Article
- Drug-Delivery System Based on Salmon DNA Nano- and Micro-Scale Structures.Scientific reports · 2017Article
- M-DNA/Transition Metal Dichalcogenide Hybrid Structure-based Bio-FET sensor with Ultra-high Sensitivity.Scientific reports · 2016Article
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Double-stranded salmon DNA (SDNA) was doped with doxorubicin hydrochloride drug molecules (DOX) to determine the binding between DOX and SDNA, and DOX optimum doping concentration in SDNA. SDNA thin films were prepared with various concentrations of DOX by drop-casting on oxygen plasma treated glass and quartz substrates. Fourier transform infrared (FTIR) spectroscopy was employed to investigate the binding sites for DOX in SDNA, and electrical and photoluminescence (PL) analyses were used to determine the optimum doping concentration of DOX. The FTIR spectra showed that up to a concentration of 30 μM of DOX, there was a tendency for binding with a periodic orientation via intercalation between nucleosides. The current and PL intensity increased as the DOX concentration increased up to 30 μM, and then as the concentration of DOX further increased, we observed a decrease in current as well as PL quenching. Finally, the optical band gap and second band onset of the transmittance spectra were analyzed to further verify the DOX binding and optimum doping concentration into SDNA thin films as a function of the DOX concentration.
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