Evidence map›Paper›PMID 26228881›Full record

ArticleAJNR. American journal of neuroradiology2015

Hyperintense Vessels on T2-PROPELLER-FLAIR in Patients with Acute MCA Stroke: Prediction of Arterial Stenosis and Perfusion Abnormality.

S J Ahn, S H Suh, K-Y Lee, J H Kim, K-D Seo, S Lee

Open access · bronzeAbstract read
In one paragraph

Article in AJNR. American journal of neuroradiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 48 citations in OpenAlex.

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  4. Review
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  7. Significance of Magnetic Resonance Imaging (MRI) T2 Hyperintense Endo-Vessels Sign in Progressive Posterior Circulation Infarction.Medical science monitor : international medical journal of experimental and clinical research · 2018
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 3 countries.

S J AhnFrom the Departments of Radiology (S.J.A., S.H.S.).
S H SuhFrom the Departments of Radiology (S.J.A., S.H.S.) Severance Institute for Vascular and Metabolic Research (S.H.S., K.-Y.L.), Yonsei University, Seoul, Korea.ORCID http://orcid.org/0000-0002-7098-4901
K-Y LeeNeurology (K.-Y.L., J.H.K., K.-D.S.), Yonsei University College of Medicine, Seoul, Korea Severance Institute for Vascular and Metabolic Research (S.H.S., K.-Y.L.), Yonsei University, Seoul, Korea kylee@yuhs.ac.
J H KimNeurology (K.-Y.L., J.H.K., K.-D.S.), Yonsei University College of Medicine, Seoul, Korea.
K-D SeoNeurology (K.-Y.L., J.H.K., K.-D.S.), Yonsei University College of Medicine, Seoul, Korea.
S LeeGlobal Applications and Workflow (S.L.), GE Healthcare, Seoul, Korea.
Yonsei University · KRGeneral Electric (Spain) · ESResearch Institute of Radiology · BY

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeFluid-attenuated inversion recovery hyperintense vessels in stroke represent leptomeningeal collateral flow. We presumed that FLAIR hyperintense vessels would be more closely associated with arterial stenosis and perfusion abnormality in ischemic stroke on T2-PROPELLER-FLAIR than on T2-FLAIR. MATERIALS AND

methodsWe retrospectively reviewed 35 patients with middle cerebral territorial infarction who underwent MR imaging. FLAIR hyperintense vessel scores were graded according to the number of segments with FLAIR hyperintense vessels in the MCA ASPECTS areas. We compared the predictability of FLAIR hyperintense vessels between T2-PROPELLER-FLAIR and T2-FLAIR for large-artery stenosis. The interagreement between perfusion abnormality and FLAIR hyperintense vessels was assessed. In subgroup analysis (9 patients with MCA horizontal segment occlusion), the association of FLAIR hyperintense vessels with ischemic lesion volume and perfusion abnormality volume was evaluated.

resultsFLAIR hyperintense vessel scores were significantly higher on T2-PROPELLER-FLAIR than on T2-FLAIR (3.50 ± 2.79 versus 1.21 ± 1.47, P < .01), and the sensitivity for large-artery stenosis was significantly improved on T2-PROPELLER-FLAIR (93% versus 68%, P = .03). FLAIR hyperintense vessels on T2-PROPELLER-FLAIR were more closely associated with perfusion abnormalities than they were on T2-FLAIR (κ = 0.64 and κ = 0.27, respectively). In subgroup analysis, FLAIR hyperintense vessels were positively correlated with ischemic lesion volume on T2-FLAIR, while the mismatch of FLAIR hyperintense vessels between the 2 sequences was negatively correlated with ischemic lesion volume (P = .01).

conclusionsIn MCA stroke, FLAIR hyperintense vessels were more prominent on T2-PROPELLER-FLAIR compared with T2-FLAIR. In addition, FLAIR hyperintense vessels on T2-PROPELLER-FLAIR have a significantly higher sensitivity for predicting large-artery stenosis than they do on T2-FLAIR. Moreover, the areas showing FLAIR hyperintense vessels on T2-PROPELLER-FLAIR were more closely associated with perfusion abnormality than those on T2-FLAIR.

Indexed as

AgedFemaleHumansInfarction, Middle Cerebral ArteryMagnetic Resonance ImagingMaleMiddle AgedPerfusionRetrospective Studies

Identifiers

PMID26228881
PMCPMC7964874
OpenAlexW1824168221

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.