Evidence map›Paper›PMID 26228877›Full record

ArticleAJNR. American journal of neuroradiology2015

Carotid Webs and Recurrent Ischemic Strokes in the Era of CT Angiography.

P M C Choi, D Singh, A Trivedi, E Qazi, D George, J Wong, A M Demchuk, M Goyal, M D Hill, B K Menon

Open access · hybridAbstract read
In one paragraph

Article in AJNR. American journal of neuroradiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 97 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
97citing papers in PubMed, 1 pooled it
8.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

97 citing papers in PubMed, 1 synthesis or guideline pooled it, 235 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Safety and efficacy of staged bilateral carotid artery stenting for bilateral carotid webs.Journal of cerebrovascular and endovascular neurosurgery · 2026
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Cerebrovascular fibromuscular dysplasia.Therapeutic advances in neurological disorders · 2026
    Review
  18. Review
  19. Observational
  20. Article

37 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 3 countries.

P M C ChoiFrom the Calgary Stroke Program, Department of Clinical Neuroscience (P.M.C.C., D.S., A.T., E.Q., J.W., A.M.D., M.G., M.D.H., B.K.M.).
D SinghFrom the Calgary Stroke Program, Department of Clinical Neuroscience (P.M.C.C., D.S., A.T., E.Q., J.W., A.M.D., M.G., M.D.H., B.K.M.).
A TrivediFrom the Calgary Stroke Program, Department of Clinical Neuroscience (P.M.C.C., D.S., A.T., E.Q., J.W., A.M.D., M.G., M.D.H., B.K.M.).
E QaziFrom the Calgary Stroke Program, Department of Clinical Neuroscience (P.M.C.C., D.S., A.T., E.Q., J.W., A.M.D., M.G., M.D.H., B.K.M.).ORCID http://orcid.org/0000-0003-0222-3884
D GeorgeDepartments of Pathology and Laboratory Medicine (D.G.).
J WongFrom the Calgary Stroke Program, Department of Clinical Neuroscience (P.M.C.C., D.S., A.T., E.Q., J.W., A.M.D., M.G., M.D.H., B.K.M.) Radiology (J.W., A.M.D., M.G., M.D.H., B.K.M.).
A M DemchukFrom the Calgary Stroke Program, Department of Clinical Neuroscience (P.M.C.C., D.S., A.T., E.Q., J.W., A.M.D., M.G., M.D.H., B.K.M.) Radiology (J.W., A.M.D., M.G., M.D.H., B.K.M.) Hotchkiss Brain Institute (A.M.D., M.G., M.D.H., B.K.M.), Calgary, Alberta, Canada.
M GoyalFrom the Calgary Stroke Program, Department of Clinical Neuroscience (P.M.C.C., D.S., A.T., E.Q., J.W., A.M.D., M.G., M.D.H., B.K.M.) Radiology (J.W., A.M.D., M.G., M.D.H., B.K.M.) Hotchkiss Brain Institute (A.M.D., M.G., M.D.H., B.K.M.), Calgary, Alberta, Canada.
M D HillFrom the Calgary Stroke Program, Department of Clinical Neuroscience (P.M.C.C., D.S., A.T., E.Q., J.W., A.M.D., M.G., M.D.H., B.K.M.) Radiology (J.W., A.M.D., M.G., M.D.H., B.K.M.) Medicine and Community Health Science (M.D.H.), University of Calgary, Calgary, Alberta, Canada Hotchkiss Brain Institute (A.M.D., M.G., M.D.H., B.K.M.), Calgary, Alberta, Canada.ORCID http://orcid.org/0000-0002-6269-1543
B K MenonFrom the Calgary Stroke Program, Department of Clinical Neuroscience (P.M.C.C., D.S., A.T., E.Q., J.W., A.M.D., M.G., M.D.H., B.K.M.) Radiology (J.W., A.M.D., M.G., M.D.H., B.K.M.) Hotchkiss Brain Institute (A.M.D., M.G., M.D.H., B.K.M.), Calgary, Alberta, Canada. Bijoy.Menon@Albertahealthservices.ca.
MACOM (United States) · USMahindra and Mahindra Limited (India) · INPediatrics and Genetics · USUniversity of Calgary · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeCarotid webs may cause recurrent ischemic stroke. We describe the prevalence, demographics, clinical presentation, imaging features, histopathology, and stroke risk associated with this under-recognized lesion. MATERIALS AND

methodsA carotid web was defined on CTA as a thin intraluminal filling defect along the posterior wall of the carotid bulb just beyond the carotid bifurcation on oblique sagittal section CTA that was seen as a septum on axial CTA. Using a prospective case series from April 2013 to April 2014, we describe the demographics, spectrum of imaging features on CTA, and histopathology of these carotid webs. From a retrospective analysis of patients at our center from May 2012 to April 2013 who had a baseline head and neck CTA followed by a brain MR imaging within 1-2 days of the CTA, we determine the period prevalence of carotid webs and the prevalence of ipsilateral stroke on imaging.

resultsIn the prospective series, the mean age was 50 years (range, 41-55 years); 5/7 patients were women. Recurrent stroke was seen in 5/7 (71.4%) patients with the carotid web; time to recurrence ranged from 1 to 97 months. Histopathology suggested a high probability of fibromuscular dysplasia. In the retrospective series, carotid webs were seen in 7/576 patients for a hospital-based-period prevalence of 1.2% (95% CI, 0.4%-2.5%). Two of these 7 patients had acute stroke in the vascular territory of the carotid web.

conclusionsA carotid web may contribute to recurrent ischemic stroke in patients with no other determined stroke mechanism. Intimal variant fibromuscular dysplasia is the pathologic diagnosis in most cases. The prevalence of carotid web is low, while the optimal management strategy remains unknown.

Indexed as

AdultCarotid Artery DiseasesCarotid Artery, InternalCerebral AngiographyFemaleHumansMaleMiddle AgedProspective StudiesRecurrenceRetrospective StudiesStrokeTomography, X-Ray Computed

Identifiers

PMID26228877
PMCPMC7964886
OpenAlexW1809968609

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.