Trial reportThe Laryngoscope2016
REMODEL larger cohort with long-term outcomes and meta-analysis of standalone balloon dilation studies.
Trial report in The Laryngoscope, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01525849 (Randomized Evaluation of Maxillary Antrostomy Versus Ostial Dilation Efficacy Through Long-Term Follow-Up), which is not on this map. Cited by 15 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Randomized Evaluation of Maxillary Antrostomy Versus Ostial Dilation Efficacy Through Long-Term Follow-Up
Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 52 citations in OpenAlex.
- Balloon Sinus Dilation Versus Functional Endoscopic Sinus Surgery for Chronic Rhinosinusitis: Systematic Review and Meta-Analysis.The Annals of otology, rhinology, and laryngology · 2023Pooled it
- A Randomized Controlled Trial of Balloon Dilation as a Treatment for Persistent Eustachian Tube Dysfunction With 1-Year Follow-Up.Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology · 2018Trial
- Middle Meatal Spacers for Synechiae Prevention Following Endoscopic Sinus Surgery: An Updated Systematic Review and Meta-Analysis of Randomized Controlled Trials.Laryngoscope investigative otolaryngology · 2026Review
- Comparison of Long-Term Revision Rates and Health Care Utilization Between Standalone Balloon Sinus Dilation and Endoscopic Sinus Surgery in Chronic Rhinosinusitis Patients Without Nasal Polyps: Is the Balloon Value Proposition Overinflated?American journal of rhinology & allergy · 2026Article
- Short- and long-term costs of sinus balloon sinuplasty and middle meatal antrostomy.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2025Article
- Artificial intelligence optimizes the standardized diagnosis and treatment of chronic sinusitis.Frontiers in physiology · 2025Review
- Efficiency of Different Approaches in Functional Endoscopic Sinus Surgery for Chronic Rhinosinusitis: A Comparative Study.Journal of pharmacy & bioallied sciences · 2024Article
- Treatment Strategy of Uncontrolled Chronic Rhinosinusitis with Nasal Polyps: A Review of Recent Evidence.International journal of molecular sciences · 2023Review
- Review
- Awake Rhinology Surgery in Response to the COVID-19 Pandemic in Europe.ORL; journal for oto-rhino-laryngology and its related specialties · 2022Review
- Current and Future Treatments of Rhinitis and Sinusitis.The journal of allergy and clinical immunology. In practice · 2020Review
- The XprESS Multi-Sinus Dilation System for the Treatment of Chronic Sinusitis: A NICE Medical Technology Guidance.Applied health economics and health policy · 2017Review
- Survey of Current Practice Patterns in the Management of Frontal Sinus Fractures.Craniomaxillofacial trauma & reconstruction · 2017Article
- Evidence and evidence gaps in therapies of nasal obstruction and rhinosinusitis.GMS current topics in otorhinolaryngology, head and neck surgery · 2016Review
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectives/hypothesisTo provide the final results from the REMODEL (randomized evaluation of maxillary antrostomy versus ostial dilation efficacy through long-term follow-up) full-study cohorts and perform meta-analyses of standalone balloon sinus dilation studies to explore long-term outcomes in a large patient sample. STUDY
designRandomized controlled trial and meta-analysis.
methodsFinal outcomes from the REMODEL randomized trial, including a larger cohort of 135 patients treated with functional endoscopic sinus surgery (FESS) or in-office balloon dilation, were evaluated. One hundred thirty patients had 12-month data, 66 had 18-month data, and 25 had 24-month data. In addition, a meta-analysis evaluated outcomes from six studies including 358 standalone balloon dilation patients with up to 24 months follow-up.
resultsOutcomes out to 2 years from the REMODEL full-study cohort are consistent with 6-month and 12-month outcomes. In the meta-analysis of standalone balloon dilation studies, technical success is 97.5%, and mean 20-item Sino-Nasal Outcomes Test scores are significantly and clinically improved at all time points (P < .0001). There are significant reductions (P < .0001) in work/school days missed, homebound days, physician/nurse visits, acute infections, and antibiotic prescriptions. Mean recovery time is 1.4 days. Comparison of 12-month symptom improvements and revision rates between the REMODEL FESS arm (n = 59), REMODEL balloon dilation arm (n = 71), and pooled single-arm standalone balloon dilation studies (n = 243) demonstrated no statistical difference.
conclusionsAll outcomes are comparable between FESS and balloon dilation at all time points from 6 months to 24 months. Balloon dilation produces faster recovery, less postoperative pain, and fewer debridements than FESS. There is significant, durable benefit in a large series of 358 patients undergoing standalone balloon dilation.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.