ReviewEuropean journal of neurology2016
Early prognostication markers in cardiac arrest patients treated with hypothermia.
Review in European journal of neurology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
16 citing papers in PubMed.
- Cerebrospinal Creatine Kinase BB Isoenzyme: A Biomarker for Predicting Outcome After Cardiac Arrest.Neurocritical care · 2025Article
- Quantitative EEG reactivity induced by electrical stimulation predicts good outcome in comatose patients after cardiac arrest.Annals of intensive care · 2024Article
- Performance of the systemic immune-inflammation index in predicting survival to discharge in out-of-hospital cardiac arrest.Resuscitation plus · 2023Article
- Circular RNAs to predict clinical outcome after cardiac arrest.Intensive care medicine experimental · 2022Article
- Targeted temperature management and early neuro-prognostication after cardiac arrest.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2021Review
- Association between Novel Marker (Platelet-Lymphocyte Ratio, Neutrophil-Lymphocyte Ratio, and Delta Neutrophil Index) and Outcomes in Sudden Cardiac Arrest Patients.Emergency medicine international · 2021Article
- Positron Emission Tomography After Ischemic Brain Injury: Current Challenges and Future Developments.Translational stroke research · 2020Review
- Somatosensory Evoked Potentials and Neuroprognostication After Cardiac Arrest.Neurocritical care · 2020Review
- Does Combining Biomarkers and Brain Images Provide Improved Prognostic Predictive Performance for Out-Of-Hospital Cardiac Arrest Survivors before Target Temperature Management?Journal of clinical medicine · 2020Article
- Distinct predictive values of current neuroprognostic guidelines in post-cardiac arrest patients.Resuscitation · 2019Article
- Quantitative measures of EEG for prediction of outcome in cardiac arrest subjects treated with hypothermia: a literature review.Journal of clinical monitoring and computing · 2018Review
- Targeted Temperature Management and Multimodality Monitoring of Comatose Patients After Cardiac Arrest.Frontiers in neurology · 2018Review
- Pathophysiology and the Monitoring Methods for Cardiac Arrest Associated Brain Injury.International journal of molecular sciences · 2017Review
- Brain Monitoring in Critically Neurologically Impaired Patients.International journal of molecular sciences · 2016Review
- Medical management of epileptic seizures: challenges and solutions.Neuropsychiatric disease and treatment · 2016Review
- Electrophysiological Monitoring of Brain Injury and Recovery after Cardiac Arrest.International journal of molecular sciences · 2015Review
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
background and purposeEstablished prognostication markers, such as clinical findings, electroencephalography (EEG) and biochemical markers, used by clinicians to predict neurological outcome after cardiac arrest (CA) are altered under therapeutic hypothermia (TH) conditions and their validity remains uncertain.
methodsMEDLINE and Embase were searched for evidence on the current standards for neurological outcome prediction for out-of-hospital CA patients treated with TH and the validity of a wide range of prognostication markers. Relevant studies that suggested one or several established biomarkers and multimodal approaches for prognostication are included and reviewed.
resultsWhilst the prognostic accuracy of various tests after TH has been questioned, pupillary light reflexes and somatosensory evoked potentials are still strongly associated with negative outcome for early prognostication. Increasingly, EEG background activity has also been identified as a valid predictor for outcome after 72 h after CA and a preferred prognostic method in clinical settings. Neuroimaging techniques, such as magnetic resonance imaging and computed tomography, can identify functional and structural brain injury but are not readily available at the patient's bedside because of limited availability and high costs.
conclusionsA multimodal algorithm composed of neurological examination, EEG-based quantitative testing and somatosensory evoked potentials, in conjunction with newer magnetic resonance imaging sequences, if available, holds promise for accurate prognostication in CA patients treated with TH. In order to avoid premature withdrawal of care, prognostication should be performed more than 72 h after CA.
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