Evidence map›Paper›PMID 26228401›Full record

ArticleJournal of psychiatric research2015

Is risk-taking propensity a familial vulnerability factor for alcohol use? An examination in two independent samples.

Stephanie M Gorka, Huiting Liu, Daniel Klein, Stacey B Daughters, Stewart A Shankman

Open access · greenAbstract read
In one paragraph

Article in Journal of psychiatric research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Error-related neural activity and alcohol use disorder: Differences from risk to remission.Progress in neuro-psychopharmacology & biological psychiatry · 2019
    Article
  5. Article
  6. Article
  7. Blunted reward processing in remitted melancholic depression.Clinical psychological science : a journal of the Association for Psychological Science · 2017
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Stephanie M GorkaUniversity of Illinois at Chicago, Department of Psychology, 1007 West Harrison St. (M/C 285), Chicago, IL 60657, USA.
Huiting LiuUniversity of Illinois at Chicago, Department of Psychology, 1007 West Harrison St. (M/C 285), Chicago, IL 60657, USA.
Daniel KleinStony Brook University, Department of Psychology, Stony Brook, NY 11794, USA.
Stacey B DaughtersUniversity of North Carolina, Chapel Hill, Department of Psychology, 247 Davie Hall, Chapel Hill, NC 27599, USA.
Stewart A ShankmanUniversity of Illinois at Chicago, Department of Psychology, 1007 West Harrison St. (M/C 285), Chicago, IL 60657, USA. Electronic address: stewarts@uic.edu.
University of Illinois Chicago · USStony Brook University · USUniversity of North Carolina at Chapel Hill · US

Funding

Minority Populations Prevention Researcher TrainingR25HD045810 · NICHD · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI NEILANDS, TORSTEN BRIAN · 2003 to 2018
$4.3M
Family Study of Reward and Threat Sensitivity in Internalizing PsychopathologyR01MH098093 · NIMH · UNIVERSITY OF ILLINOIS AT CHICAGO · PI SHANKMAN, STEWART AARON · 2012 to 2015
$2.7M
Distress Tolerance and Adolescent Substance UseR21DA022741 · NIDA · UNIV OF MARYLAND, COLLEGE PARK · PI DAUGHTERS, STACEY B · 2007 to 2008
$409k
Response to Unpredictable Threat in Alcohol Dependence and Panic DisorderF31AA022273 · NIAAA · UNIVERSITY OF ILLINOIS AT CHICAGO · PI GORKA, STEPHANIE · 2013 to 2015
$85k
NIAAA NIH HHS F31 AA022273NIAAA NIH HHS F31 AA 22273-01A1NICHD NIH HHS R25 HD045810NIDA NIH HHS R21 DA022741NIMH NIH HHS R01 MH098093
6 · The paper itself

Abstract

Research indicates that increased risk-taking propensity (RTP) is associated with higher alcohol use. There is also some evidence to suggest that it is not just a state factor or 'scar,' but instead a vulnerability factor. If this is the case, increased RTP should be evident in healthy individuals that are at risk for alcohol use. To date, few studies have examined whether RTP is a familial vulnerability factor and thus, the aim of the current study was to test whether RTP aggregates within families and if increased RTP is evident in biological family members at risk for alcohol use. Sample 1 included 87 biological, adult sibling pairs and Sample 2 included 111 biological mother and adolescent dyads (total N = 396). All participants completed a behavioral measure of RTP and were assessed for alcohol use. Results in both samples were strikingly consistent. In Sample 1, RTP was correlated among siblings and greater frequency of proband alcohol use predicted greater sibling RTP, over and above sibling alcohol use. In Sample 2, RTP was correlated among mothers and their offspring and greater maternal alcohol use problems predicted greater adolescent RTP over and above adolescent substance use. Together, these findings suggest that RTP may be a familial vulnerability factor for alcohol use as it aggregates within families and is increased in relatives of individuals with higher levels of alcohol use.

Indexed as

Family HealthRisk-TakingAdolescentAdultAlcohol DrinkingFemaleHumansIndividualityMaleMiddle AgedMothersSiblingsSubstance-Related DisordersYoung AdultAlcohol useRisk-taking propensityVulnerability factor

Identifiers

PMID26228401
PMCPMC4522043
OpenAlexW2104767387

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.