ArticleEnvironmental geochemistry and health2016
Hair elements and healthy aging: a cross-sectional study in Hainan Island, China.
Article in Environmental geochemistry and health, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.
- A systematic review of diet and medication use among centenarians and near-centenarians worldwide.GeroScience · 2024Pooled it
- Hainan Longevity Model, Senile Degeneration, Cognitive Disability and Healthy Longevity.Aging medicine (Milton (N.S.W)) · 2026Review
- Metals and metalloids concentrations in adults aged 50 and older from Mexico.Research square · 2025Article
- Arsenic, mercury, manganese, and lead exposure in Mexican adults aged 50 and older.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2025Article
- Investigation on the Association of Copper and Copper-to-Zinc-Ratio in Hair with Acute Coronary Syndrome Occurrence and Its Risk Factors.Nutrients · 2022Article
- An Evaluation of Different Digestion Methods for the Quantitation of Inorganic Elements in Human Hair Using ICP-MS.Journal of analytical methods in chemistry · 2022Article
- Factors Influencing Selenium Concentration in Community-Dwelling Patients with Type 2 Diabetes Mellitus.Biological trace element research · 2021Article
- Links between Cognitive Status and Trace Element Levels in Hair for an Environmentally Exposed Population: A Case Study in the Surroundings of the Estarreja Industrial Area.International journal of environmental research and public health · 2019Article
- Human predisposition to cognitive impairment and its relation with environmental exposure to potentially toxic elements.Environmental geochemistry and health · 2018Article
- Relationships among Environment, Climate, and Longevity in China.International journal of environmental research and public health · 2017Article
- Indicative and complementary effects of human biological indicators for heavy metal exposure assessment.Environmental geochemistry and health · 2017Article
- Demographics, phenotypic health characteristics and genetic analysis of centenarians in China.Mechanisms of ageing and development · 2017Review
Corrections and comments
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Authors and funding
6 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Healthy aging is considered as the core issue of aging population. Centenarians are a symbol of healthy aging. Concentration of elements in hair is an indicator of micronutrient status, which can affect the human health. In the present study, we investigated element concentrations in the scalp hair of 255 healthy centenarians from Hainan Island, China. The pattern of intergenerational transmission of elements and the effects of confounders such as sex, age, education level, smoking habits, alcohol intake, and frequency of hospitalization on hair element concentrations were assessed. For most elements, the load in hair increased significantly through intergenerational transmission (i.e., centenarians < children < grandchildren). Our results also demonstrated that female centenarians had significantly higher concentrations of Ca, Mg, Mn, Se, and Sr but lower levels of Cr and P. The Mn level was statistically significantly lower in the primary studies group. Alcohol intake was positively associated with Cd and Na levels, whereas smoking habits showed no significant effect on all the elements. Furthermore, the frequency of hospitalization was significantly positively associated with Cd, Cu, and Pb concentration. Moreover, our analysis suggested that adequate concentrations of Fe and Se might increase the life span of centenarians, whereas excessive concentrations of P and Pb were harmful to health and reduced life span. These results imply that element concentrations could be manipulated as a therapeutic modality in geriatric disease. They might also provide reference values for diseased subjects, allowing improved diagnoses and more effective therapies, which might support effective policies on health and aging.
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