Evidence map›Paper›PMID 26228164›Full record

Trial reportPsychiatry research2015

Course of symptom change during anxiety treatment: Reductions in anxiety and depression in patients completing the Coordinated Anxiety Learning and Management program.

Jessica Bomyea, Ariel Lang, Michelle G Craske, Denise A Chavira, Cathy D Sherbourne, Raphael D Rose, Daniela Golinelli, Laura Campbell-Sills, Stacy S Welch, Greer Sullivan and 3 more

Abstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Psychiatry research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Jessica BomyeaDepartment of Psychiatry, University of California, San Diego, La Jolla, CA, USA. Electronic address: bomyea@hotmail.com.
Ariel LangDepartment of Psychiatry, University of California, San Diego, La Jolla, CA, USA; VA San Diego Health Care System Center of Excellence for Stress and Mental Health, San Diego, La Jolla, CA, USA.
Michelle G CraskeDepartment of Psychology, University of California, Los Angeles, CA, USA.
Denise A ChaviraDepartment of Psychology, University of California, Los Angeles, CA, USA.
Cathy D SherbourneRAND Corporation, Santa Monica, CA, USA.
Raphael D RoseDepartment of Psychology, University of California, Los Angeles, CA, USA.
Daniela GolinelliRAND Corporation, Santa Monica, CA, USA.
Laura Campbell-SillsDepartment of Psychiatry, University of California, San Diego, La Jolla, CA, USA.
Stacy S WelchDepartment of Psychiatry and Behavioral Sciences, University of Washington School of Medicine and Harborview Center for Healthcare Improvement for Addictions, Mental Illness, and Medically Vulnerable Populations (CHAMMP), Seattle, WA, USA.
Greer SullivanRAND Corporation, Santa Monica, CA, USA; Department of Psychiatry, University of California, Riverside, USA; VA South Central Mental Illness Research, Education, and Clinical Center University of Arkansas for Medical Sciences, Little Rock, AR, USA.
Alexander BystritskyPsychiatry and Biobehavioral Sciences, David Geffen School of Medicine, University of California, Los Angeles, CA, USA.
Peter Roy-ByrneDepartment of Psychiatry and Behavioral Sciences, University of Washington School of Medicine and Harborview Center for Healthcare Improvement for Addictions, Mental Illness, and Medically Vulnerable Populations (CHAMMP), Seattle, WA, USA.
Murray B SteinDepartment of Psychiatry, University of California, San Diego, La Jolla, CA, USA; Department of Family Medicine and Public Health, University of California, San Diego, La Jolla, CA, USA.

Funding

CALM: Improving Primary Care Anxiety OutcomesU01MH057835 · NIMH · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI STEIN, MURRAY B. · 2005 to 2009
$3.3M
CALM: IMPROVING PRIMARY CARE ANXIETY OUTCOMESU01MH070018 · NIMH · RAND CORPORATION · PI SHERBOURNE, CATHY D · 2005 to 2009
$3.1M
CALM: Improving Primary Care Anxiety OutcomesU01MH058915 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI CRASKE, MICHELLE G · 2005 to 2009
$3.0M
CALM: Improving Primary Care OutcomesU01MH057858 · NIMH · UNIVERSITY OF WASHINGTON · PI ROY-BYRNE, PETER PAUL · 2005 to 2009
$2.4M
CALM: Improving Primary Care Anxiety OutcomesU01MH070022 · NIMH · UNIV OF ARKANSAS FOR MED SCIS · PI SULLIVAN, JAN GREER · 2005 to 2009
$2.3M
Improving Patient Outcomes in Anxiety DisordersK24MH064122 · NIMH · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI STEIN, MURRAY B. · 2001 to 2011
$1.3M
Treating Anxiety in Public Sector Medical SettingsK24MH065324 · NIMH · UNIVERSITY OF WASHINGTON · PI ROY-BYRNE, PETER PAUL · 2003 to 2007
$661k
Evaluating a novel working memory training program to decrease symptoms of PTSDF31MH088170 · NIMH · SAN DIEGO STATE UNIVERSITY · PI BOMYEA, JESSICA · 2009 to 2013
$119k
NIMH NIH HHS F31 MH088170NIMH NIH HHS F31MH0881704NIMH NIH HHS K24 MH064122NIMH NIH HHS K24 MH065324NIMH NIH HHS K24MH065324NIMH NIH HHS K24MH64122NIMH NIH HHS U01 MH057835NIMH NIH HHS U01MH057835NIMH NIH HHS U01 MH057858NIMH NIH HHS U01MH057858NIMH NIH HHS U01 MH058915NIMH NIH HHS U01MH058915NIMH NIH HHS U01 MH070018NIMH NIH HHS U01MH070018NIMH NIH HHS U01 MH070022NIMH NIH HHS U01MH070022
6 · The paper itself

Abstract

When treating anxious patients with co-occurring depression, research demonstrates that both types of symptoms independently improve. The current analyses examined how reductions in anxiety and depression may be interrelated both during treatment, as well as over time following treatment. Participants were 503 individuals with one or more DSM-IV anxiety disorders who completed a collaborative care anxiety management program. Anxiety and depression were assessed at each treatment session (i.e., session by session data) and also at 6, 12, and 18-month post-baseline assessments (i.e., long-term outcomes data). Mediation analyses examined changes in symptoms in session by session data and long-term outcomes data. Anxiety and depression changed reciprocally in session by session data; change in anxiety mediated change in depression to a greater extent than vice versa. In the long-term outcomes data, change in anxiety mediated change in depression. However, the reverse mediation model of the long-term outcomes period revealed that accounting for changes in depression altered the effect of time on anxiety. Thus, temporal change during active treatment may share similarities with those related to maintaining gains after treatment, although differences arose in the reverse mediation models. Limitations of the methodology and implications of anxiety treatment for depression outcomes are discussed.

Indexed as

Disease ManagementLearningAdultAnxietyCognitive Behavioral TherapyDepressionFemaleHumansMaleMiddle AgedTreatment OutcomeAnxietyCBTDepressionMediationTreatment

Identifiers

PMID26228164
PMCPMC4656042

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.