Evidence map›Paper›PMID 26228057›Full record

ReviewThe British journal of nutrition2015

Low-grade inflammation, diet composition and health: current research evidence and its translation.

Anne M Minihane, Sophie Vinoy, Wendy R Russell, Athanasia Baka, Helen M Roche, Kieran M Tuohy, Jessica L Teeling, Ellen E Blaak, Michael Fenech, David Vauzour and 7 more

2 registry-linked trialsOpen access · hybridAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in The British journal of nutrition, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 441 papers, 13 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
441citing papers in PubMed, 13 pooled it
25.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03577119 nacompletednot on this mapstarted 2018, after this paper: background citation

Full-fat Yogurt and Glucose Tolerance

TypeinterventionalSponsorUniversity of Vermont Medical CenterRan2018 to 2022Enrolled13ConditionsPre-DiabetesArmsFull-fat yogurt, Non-fat yogurt
NCT05349227 narecruitingnot on this mapstarted 2022, after this paper: background citation

Comprehensive Outcomes for After Cancer Health (COACH): the Feasibility and Impact of an MHealth Augmented Coaching Program for Self-Management in Cancer Survivors

TypeinterventionalSponsorPack HealthRan2022 to 2027Enrolled625ConditionsOvarian Cancer, Breast Cancer, Lung Cancer, Gastric CancerArmsDigital Health Coaching Program, Fitbit
3 · Its place in the literature

Who cites it

441 citing papers in PubMed, 13 syntheses or guidelines pooled it, 880 citations in OpenAlex.

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381 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

17 authors at 12 institutions in 6 countries.

Anne M MinihaneDepartment of Nutrition,Norwich Medical School, University of East Anglia,NorwichNR4 7TJ,UK.
Sophie VinoyMondelēz International - R&D, Nutrition Department,91400Saclay,France.
Wendy R RussellRowett Institute of Nutrition and Health, University of Aberdeen,AberdeenAB21 9SB,UK.
Athanasia BakaFormerly ILSI Europe a.i.s.b.l.,Avenue E. Mounier 83, Box 6,B-1200Brussels,Belgium.
Helen M RocheNutrigenomics Research Group, UCD Institute of Food and Health and UCD Conway Institute, Belfield, University College Dublin,Dublin 4,Republic of Ireland.
Kieran M TuohyDepartment of Food Quality and Nutrition,Research and Innovation Centre, Fondazione Edmund Mach, San Michele all'Adige,38010Trento,Italy.
Jessica L TeelingCentre for Biological Sciences, Faculty of Natural and Environmental Sciences, University of Southampton,SouthamptonSO16 6YD,UK.
Ellen E BlaakDepartment of Human Biology,NUTRIM School for Nutrition, Toxicology and Metabolism, Maastricht University,Maastricht,The Netherlands.
Michael FenechNutrigenomics and Neurodegenerative Disease Prevention, Preventative Health Flagship, CSIRO, Animal, Food and Health Sciences,Adelaide,Australia.
David VauzourDepartment of Nutrition,Norwich Medical School, University of East Anglia,NorwichNR4 7TJ,UK.
Harry J McArdleRowett Institute of Nutrition and Health, University of Aberdeen,AberdeenAB21 9SB,UK.
Bas H A KremerMicrobiology and Systems Biology, TNO, Zeist,3704HE,The Netherlands.
Luc SterkmanNewtricious R&D B.V., Oirlo,5808AL,The Netherlands.
Katerina VafeiadouSchool of Life and Medical Sciences, University of Hertfordshire,HatfieldAL10 9AB,UK.
Massimo Massi BenedettiDepartment of Internal Medicine,University of Perugia,Perugia,Italy.
Christine M WilliamsHugh Sinclair Unit of Human Nutrition, Department of Food and Nutritional Sciences, University of Reading,ReadingRG6 6AP,UK.
Philip C CalderFaculty of Medicine, University of Southampton,SouthamptonSO16 6YD,UK.
University of Aberdeen · GBUniversity of East Anglia · GBCommonwealth Scientific and Industrial Research Organisation · AUFondazione Edmund Mach · ITInternational Life Sciences Institute Europe · BEMaastricht University · NLNIHR Southampton Biomedical Research Centre · GBUniversity College Dublin · IEUniversity of Hertfordshire · GBUniversity of Perugia · ITUniversity of Reading · GBUniversity of Southampton · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The importance of chronic low-grade inflammation in the pathology of numerous age-related chronic conditions is now clear. An unresolved inflammatory response is likely to be involved from the early stages of disease development. The present position paper is the most recent in a series produced by the International Life Sciences Institute's European Branch (ILSI Europe). It is co-authored by the speakers from a 2013 workshop led by the Obesity and Diabetes Task Force entitled 'Low-grade inflammation, a high-grade challenge: biomarkers and modulation by dietary strategies'. The latest research in the areas of acute and chronic inflammation and cardiometabolic, gut and cognitive health is presented along with the cellular and molecular mechanisms underlying inflammation-health/disease associations. The evidence relating diet composition and early-life nutrition to inflammatory status is reviewed. Human epidemiological and intervention data are thus far heavily reliant on the measurement of inflammatory markers in the circulation, and in particular cytokines in the fasting state, which are recognised as an insensitive and highly variable index of tissue inflammation. Potential novel kinetic and integrated approaches to capture inflammatory status in humans are discussed. Such approaches are likely to provide a more discriminating means of quantifying inflammation-health/disease associations, and the ability of diet to positively modulate inflammation and provide the much needed evidence to develop research portfolios that will inform new product development and associated health claims.

Indexed as

DietBiomarkersCardiovascular DiseasesChronic DiseaseDiabetes Mellitus, Type 2Dietary CarbohydratesDietary FatsHumansInflammationMetabolic SyndromeObesityPublic HealthBiomarkersDietary CarbohydratesDietary FatsBiomarkersChronic diseasesHealth claimsLow-grade inflammation

Identifiers

PMID26228057
PMCPMC4579563
OpenAlexW2155379427

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.