Evidence map›Paper›PMID 26227740›Full record

ArticleTravel medicine and infectious disease

Imported malaria in pregnant women: A retrospective pooled analysis.

Annina K Käser, Paul M Arguin, Peter L Chiodini, Valerie Smith, Jean Delmont, Beatriz C Jiménez, Anna Färnert, Mikio Kimura, Michael Ramharter, Martin P Grobusch and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Travel medicine and infectious disease. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Temporal trends of gestational malaria in the United States.Parasite epidemiology and control · 2020
    Article
  5. Review
  6. Malaria in the pregnant traveler.Journal of travel medicine · 2020
    Article
  7. Review
  8. Observational
  9. Article
  10. Article
  11. Recrudescence ofThe American journal of tropical medicine and hygiene · 2017
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Annina K KäserUniversity of Zürich Travel Clinic, Infectious Diseases, Institute for Epidemiology, Biostatistics and Prevention, University of Zurich, Hirschengraben 84, 8001 Zurich, Switzerland.
Paul M ArguinDivision of Parasitic Diseases and Malaria, Center for Global Health, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Peter L ChiodiniPublic Health England, Malaria Reference Laboratory, London School of Hygiene & Tropical Medicine, London, UK; Department of Clinical Parasitology, Hospital for Tropical Diseases, University College London Hospitals, NHS Foundation Trust, London, UK.
Valerie SmithPublic Health England, Malaria Reference Laboratory, London School of Hygiene & Tropical Medicine, London, UK.
Jean DelmontUniversity Hospital Institute for Infectious and Tropical Diseases, Hospital Nord, AP-HM, Marseille, France.
Beatriz C JiménezDepartment of Internal Medicine, University Hospital Fuenlabrada, Madrid, Spain.
Anna FärnertUnit of Infectious Diseases, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden.
Mikio KimuraDepartment of Internal Medicine, Shin-Yamanote Hospital, Japan Anti-Tuberculosis Association, Tokyo, Japan.
Michael RamharterDepartment of Medicine I, Division of Infectious Diseases and Tropical Medicine, Medical University of Vienna, Vienna, Austria; Institute of Tropical Medicine, University of Tübingen, Tübingen, Germany.
Martin P GrobuschCentre of Tropical Medicine and Travel Medicine, Department of Infectious Diseases, Division of Internal Medicine, Academic Medical Centre, Amsterdam, The Netherlands.
Patricia SchlagenhaufUniversity of Zürich Travel Clinic, Infectious Diseases, Institute for Epidemiology, Biostatistics and Prevention, University of Zurich, Hirschengraben 84, 8001 Zurich, Switzerland. Electronic address: pat@ifspm.uzh.ch.

Funding

Intramural CDC HHS CC999999
6 · The paper itself

Abstract

backgroundData on imported malaria in pregnant women are scarce.

methodA retrospective, descriptive study of pooled data on imported malaria in pregnancy was done using data from 1991 to 2014 from 8 different collaborators in Europe, the United States and Japan. National malaria reference centres as well as specialists on this topic were asked to search their archives for cases of imported malaria in pregnancy. A total of 631 cases were collated, providing information on Plasmodium species, region of acquisition, nationality, country of residence, reason for travel, age, gestational age, prophylactic measures and treatment used, as well as on complications and outcomes in mother and child.

resultsDatasets from some sources were incomplete. The predominant Plasmodium species was P. falciparum (78.5% of cases). Among the 542 cases where information on the use of chemoprophylaxis was known, 464 (85.6%) did not use chemoprophylaxis. The main reason for travelling was "visiting friends and relatives" VFR (57.8%) and overall, most cases of malaria were imported from West Africa (57.4%). Severe anaemia was the most frequent complication in the mother. Data on offspring outcome were limited, but spontaneous abortion was a frequently reported foetal outcome (n = 14). A total of 50 different variants of malaria treatment regimens were reported.

conclusionsImported cases of malaria in pregnancy are mainly P. falciparum acquired in sub-Saharan Africa. Malaria prevention and treatment in pregnant travellers is a challenge for travel medicine due to few data on medication safety and maternal and foetal outcomes. International, collaborative efforts are needed to capture standardized data on imported malaria cases in pregnant women.

Indexed as

AdolescentAdultFemaleHumansMalariaMiddle AgedPregnancyPregnancy Complications, InfectiousRetrospective StudiesTravelYoung AdultChemoprophylaxisImported malariaPregnancyTravelTreatment

Identifiers

PMID26227740
PMCPMC4627431

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.