ArticlePloS one2015
Removal of Protein Capping Enhances the Antibacterial Efficiency of Biosynthesized Silver Nanoparticles.
Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 70 citations in OpenAlex.
- Antimicrobial potential of silver nanoparticles synthesized from mushroom extracts against drug-resistant pathogens.New microbes and new infections · 2026Article
- Contact-Dependent Antibacterial Performance of Silver Nanoparticles Encapsulated in Collagen-Based Gels.Journal of functional biomaterials · 2026Article
- Amino acids and related polymers-mediated versatile noble metal nanomaterials: Engineered design, antibacterial mechanisms and food preservation.Food chemistry: X · 2025Review
- A review of microbes mediated biosynthesis of silver nanoparticles and their enhanced antimicrobial activities.Heliyon · 2024Review
- Article
- Microwave Irradiation vs. Structural, Physicochemical, and Biological Features of Porous Environmentally Active Silver-Silica Nanocomposites.International journal of molecular sciences · 2023Article
- Phycotoxicity and catalytic reduction activity of green synthesized Oscillatoria gelatin-capped silver nanoparticles.Scientific reports · 2022Article
- Synthesis, purification and characterization ofRSC advances · 2022Article
- Antibacterial approaches in tissue engineering using metal ions and nanoparticles: From mechanisms to applications.Bioactive materials · 2021Review
- Insight into the Antibacterial Activity of Selected Metal Nanoparticles and Alterations within the Antioxidant Defence System inInternational journal of molecular sciences · 2021Article
- Influence of the capping of biogenic silver nanoparticles on their toxicity and mechanism of action towards Sclerotinia sclerotiorum.Journal of nanobiotechnology · 2021Article
- Impact of an Engineered Copper-Titanium Dioxide Nanocomposite and Parent Substrates on the Bacteria Viability, Antioxidant Enzymes and Fatty Acid Profiling.International journal of molecular sciences · 2020Article
- Enzyme Stability in Nanoparticle Preparations Part 1: Bovine Serum Albumin Improves Enzyme Function.Molecules (Basel, Switzerland) · 2020Article
- Zinkicide Is a ZnO-Based Nanoformulation with Bactericidal Activity against Liberibacter crescens in Batch Cultures and in Microfluidic Chambers Simulating Plant Vascular Systems.Applied and environmental microbiology · 2020Article
- Boron doped silver-copper alloy nanoparticle targeting intracellular S. aureus in bone cells.PloS one · 2020Article
- Inhibition of H1N1 influenza virus infection by zinc oxide nanoparticles: another emerging application of nanomedicine.Journal of biomedical science · 2019Article
- Green synthesis of silver nanoparticles: biomolecule-nanoparticle organizations targeting antimicrobial activity.RSC advances · 2019Review
- Evaluation of E. coli inhibition by plain and polymer-coated silver nanoparticles.Revista do Instituto de Medicina Tropical de Sao Paulo · 2018Article
- Biomimetic synthesis of AgNPs fromIET nanobiotechnology · 2017Article
- Biosynthesized Protein-Capped Silver Nanoparticles Induce ROS-Dependent Proapoptotic Signals and Prosurvival Autophagy in Cancer Cells.ACS omega · 2017Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The present study demonstrates an economical and environmental affable approach for the synthesis of "protein-capped" silver nanoparticles in aqueous solvent system. A variety of standard techniques viz. UV-visible spectroscopy, transmission electron microscopy (TEM), energy dispersive spectroscopy (EDS) and X-ray diffraction (XRD) measurements were employed to characterize the shape, size and composition of nanoparticles. The synthesized nanoparticles were found to be homogenous, spherical, mono-dispersed and covered with multi-layered protein shell. In order to prepare bare silver nanoparticles, the protein shell was removed from biogenic nanoparticles as confirmed by UV-visible spectroscopy, FTIR and photoluminescence analysis. Subsequently, the antibacterial efficacy of protein-capped and bare silver nanoparticles was compared by bacterial growth rate and minimum inhibitory concentration assay. The results revealed that bare nanoparticles were more effective as compared to the protein-capped silver nanoparticles with varying antibacterial potential against the tested Gram positive and negative bacterial species. Mechanistic studies based on ROS generation and membrane damage suggested that protein-capped and bare silver nanoparticles demonstrate distinct mode of action. These findings were strengthened by the TEM imaging along with silver ion release measurements using inductively coupled plasma atomic emission spectroscopy (ICP-AES). In conclusion, our results illustrate that presence of protein shell on silver nanoparticles can decrease their bactericidal effects. These findings open new avenues for surface modifications of nanoparticles to modulate and enhance their functional properties.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.