Trial reportJournal of perinatology : official journal of the California Perinatal Association2015
Effect of 40-cm segment umbilical cord milking on hemoglobin and serum ferritin at 6 months of age in full-term infants of anemic and non-anemic mothers.
Trial report in Journal of perinatology : official journal of the California Perinatal Association, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 42 citations in OpenAlex.
- Umbilical cord milking versus delayed cord clamping in term infants: a systematic review and meta-analysis.Journal of perinatology : official journal of the California Perinatal Association · 2021Pooled it
- "Serum ferritin levels in newborns at 3 months of life after intact umbilical cord milking versus delayed cord clamping"-a randomized controlled trial.European journal of pediatrics · 2025Trial
- The haemodynamic effects of umbilical cord milking in term infants: a randomised controlled trial.Singapore medical journal · 2023Trial
- Umbilical cord milking for neonates who are depressed at birth: a randomized trial of feasibility.Journal of perinatology : official journal of the California Perinatal Association · 2018Trial
- A Randomized Clinical Trial of Umbilical Cord Milking vs Delayed Cord Clamping in Preterm Infants: Neurodevelopmental Outcomes at 22-26 Months of Corrected Age.The Journal of pediatrics · 2018Trial
- Article
- Biomarkers of Brain Dysfunction in Perinatal Iron Deficiency.Nutrients · 2024Review
- Anemia, Iron Supplementation, and the Brain.Clinics in perinatology · 2023Review
- Reticulocyte Hemoglobin Equivalent has Comparable Predictive Accuracy as Conventional Serum Iron Indices for Predicting Iron Deficiency and Anemia in a Nonhuman Primate model of Infantile Iron Deficiency.The Journal of nutrition · 2023Article
- Review
- Prevention of iron deficiency anemia in infants and toddlers.Pediatric research · 2021Review
- Is Anemia in Low Income Pregnant Women Related to Their Infants' Having Anemia? A Cohort Study of Pregnant Women-Infant Pairs in the United States.Maternal and child health journal · 2020Article
- Milking of the Umbilical Cord in Term and Late Preterm Infants.BioMed research international · 2019Review
- [Association between iron deficiency and brain developmental disorder in children].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2018Article
- Whole blood volumes associated with milking intact and cut umbilical cords in term newborns.Journal of perinatology : official journal of the California Perinatal Association · 2018Article
- Approaches for Reducing the Risk of Early-Life Iron Deficiency-Induced Brain Dysfunction in Children.Nutrients · 2018Review
- Metabolomic analysis of CSF indicates brain metabolic impairment precedes hematological indices of anemia in the iron-deficient infant monkey.Nutritional neuroscience · 2018Article
- Italian Recommendations for Placental Transfusion Strategies.Frontiers in pediatrics · 2018Review
- Umbilical Cord Milking: A Review.Frontiers in pediatrics · 2018Review
- A quality improvement initiative for delayed umbilical cord clamping in very low-birthweight infants.BMC pediatrics · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo assess the effect of early clamping and milking of a 40-cm umbilical cord LUCM (long umbilical cord and milking) on hemoglobin (Hb) and serum ferritin concentrations at 6 months of age and to evaluate whether the effect is different in infants of anemic and non-anemic mothers. STUDY
designEligible term-infants of anemic (maternal Hb<11.0 g dl(-1)) and non-anemic mothers (Hb ⩾11.0 g dl(-1)) were randomized to LUCM or control groups (N=100 each). In the LUCM group, the umbilical cord was clamped at 40-cm length and milked. The control group had the cord clamped at 5 cm and not milked. Neonatal morbidities until discharge and Hb and serum ferritin at 6 months of age were compared. Effects in infants of anemic and non-anemic mothers were compared.
resultCompared with infants of non-anemic mothers, cord Hb was similar (14.50±1.90 g dl(-1) vs 14.67±1.73 g dl(-1)), but cord ferritin lower (85.8±55.4 ng ml(-1) vs 119.4±58.5 ng ml(-1), P<0.01) in infants of anemic mothers. Mean Hb concentration at 6 months was 9.60±1.42 g dl(-1) in the LUCM group and 9.07±1.10 g dl(-1) in the control group (P=0.004). Mean serum-ferritin concentration at 6 months was 113.9±43.8 ng ml(-1) in the LUCM group and 70.8±39.5 ng/ml in the control group (P<0.001). The effectiveness of LUCM did not vary with the maternal anemia status.
conclusionKeeping the umbilical cord long and milking may be an effective method for improving Hb and iron stores at 6 months of age in term-infants.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.