Evidence map›Paper›PMID 26225964›Full record

ReviewInternational journal of molecular sciences2015

Recent Breakthroughs in the Antioxidant and Anti-Inflammatory Effects of Morella and Myrica Species.

Bruno J C Silva, Ana M L Seca, Maria do Carmo Barreto, Diana C G A Pinto

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.

  1. Pooled it
  2. Pharmacological basis for the traditional use ofJournal of traditional and complementary medicine · 2026
    Article
  3. Valorization of Bayberry (Plants (Basel, Switzerland) · 2026
    Article
  4. Article
  5. Phytochemicals with Added Value fromMolecules (Basel, Switzerland) · 2020
    Review
  6. Article
  7. Plants (Basel, Switzerland) · 2019
    Review
  8. Diarylheptanoid Glycosides of Morella salicifolia Bark.Molecules (Basel, Switzerland) · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Bruno J C SilvaDepartment of Technological Science and Development, University of Azores, Ponta Delgada 9501-801, Portugal. 20137026@aluno.uac.pt.
Ana M L SecaDepartment of Technological Science and Development, University of Azores, Ponta Delgada 9501-801, Portugal. anaseca@uac.pt.
Maria do Carmo BarretoDepartment of Technological Science and Development, University of Azores, Ponta Delgada 9501-801, Portugal. barreto@uac.pt.
Diana C G A PintoDepartment of Chemistry & Química Orgânica Produtos Naturais and Agroalimentares, University of Aveiro, Aveiro 3810-193, Portugal. diana@ua.pt.
Universidade dos Açores · PTUniversity of Aveiro · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oxidative stress is one of the risk factors for the development of several chronic diseases, such as diabetes, cancer, cardiovascular and neurodegenerative diseases. Antioxidants are therefore highly sought and can be seen as a type of preventive medicine against several diseases. Myrica and Morella genus (Myricaceae) are taxonomically very close and their species are trees or shrubs with edible fruits that exhibit relevant uses in traditional medicine, for instance in Chinese or Japanese folk medicine they are used to treat diarrhea, digestive problems, headache, burns and skin diseases. Nearly 36 compounds were isolated from different morphological parts of Myrica and/or Morella species and their antioxidant and anti-inflammatory activities evaluated. Thirteen of these compounds exhibit greater effects than the positive controls used. Adenodimerin A was the most active compound reported (in a 2,2-diphenyl-1-picrylhydrazyl (DPPH) assay EC50= 7.9 ± 0.3 µM). These results are just one aspect of the antioxidant and anti-inflammatory evaluations reported regarding Myrica and Morella species, so a comprehensive overview on the current status, highlighting the antioxidant health promoting effect of these species, their key antioxidant compounds as well as the compounds with protective effects against oxidative stress related diseases such as inflammation, is relevant.

Indexed as

Anti-Inflammatory AgentsAntioxidantsFlavonoidsMyricaceaePlant ExtractsAnti-Inflammatory AgentsAntioxidantsFlavonoidsPlant Extractsanti-inflammatoryantioxidantdiarylheptanoidflavonoidsMorellaMyrica

Identifiers

PMID26225964
PMCPMC4581187
OpenAlexW1919523022

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.