ArticleMolecules (Basel, Switzerland)2015
Phenolic Compounds from the Roots of Rhodiola crenulata and Their Antioxidant and Inducing IFN-γ Production Activities.
Article in Molecules (Basel, Switzerland), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- Adulteration prevention-oriented systematic review of chemical constituents in the genusFrontiers in pharmacology · 2026Review
- Determination of Potential Inhibitors againstCurrent pharmaceutical design · 2026Review
- Identification of potential inhibitors againstJournal of enzyme inhibition and medicinal chemistry · 2024Article
- Bioactive Compounds fromLife (Basel, Switzerland) · 2023Review
- Inhibitory activity of flavonoids from Ephedrae Herba on hypoxia signaling in PANC-1 cells and the evaluation of their mechanisms.Journal of natural medicines · 2021Article
- Phytochemical, Antibacterial and Antioxidant Activity Evaluation ofMolecules (Basel, Switzerland) · 2020Article
- Rhodiosin and herbacetin inPharmaceutical biology · 2019Article
- Supplementation of Plants with Immunomodulatory Properties during Pregnancy and Lactation-Maternal and Offspring Health Effects.Nutrients · 2019Article
- Chemical Constituents from the Stems of Tinospora sinensis and Their Bioactivity.Molecules (Basel, Switzerland) · 2018Article
- Mitochondrial protective and anti-apoptotic effects ofNeural regeneration research · 2017Article
- Chemical Constituents from the Flower of Hosta plantaginea with Cyclooxygenases Inhibition and Antioxidant Activities and Their Chemotaxonomic Significance.Molecules (Basel, Switzerland) · 2017Article
- Recent Advances in Plant Phenolics.Molecules (Basel, Switzerland) · 2017Review
- Central additive effect of Ginkgo biloba and Rhodiola rosea on psychomotor vigilance task and short-term working memory accuracy.Journal of intercultural ethnopharmacologyArticle
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9 authors.
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Abstract
In the present study, two new phenolic compounds 1 and 11, a pair of lignan isomers 12 and 13 with their absolute configurations established for the first time, were isolated from the ethanol extract of the roots of Rhodiola crenulata, together with 13 known phenolic compounds, and their structures were elucidated via NMR, HRESIMS, UV, IR and CD analyses. All the isolated compounds were evaluated for their in vitro antioxidant activities using the 2,2-diphenyl-1-picryhydrazyl (DPPH) and 2,2'-azino-bis (3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) radical scavenging assays. Ten of them exhibited significant antioxidant activities compared to ascorbic acid. Furthermore, the inducibilities of the isolated compounds to IFN-γ production were also assessed. Compounds 1, 8, 9, 12, 13, 14 and 15 could moderately stimulate IFN-γ expression.
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