Evidence map›Paper›PMID 26225072›Full record

ArticleJournal of maxillofacial and oral surgery2015

Dexmedetomidine Supported Office Based Genioplasty: A Pilot Study.

Prashant Kumar, Kannu Priya, Shruti Kirti, Sanjay Johar, Virendra Singh

Abstract read
In one paragraph

Article in Journal of maxillofacial and oral surgery, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Prashant KumarDepartment of Anaesthesiology, PGIMS, Rohtak, Haryana India.
Kannu PriyaDepartment of Oral and Maxillofacial Surgery, PGIDS, Rohtak, India.
Shruti KirtiDepartment of Oral and Maxillofacial Surgery, PGIDS, Rohtak, India.
Sanjay JoharDepartment of Anaesthesiology, PGIMS, Rohtak, Haryana India.
Virendra SinghDepartment of Oral and Maxillofacial Surgery, PGIMS, Rohtak, Haryana India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionDespite the availability of wide variety of pharmacological agents for dental procedural sedation, there has always been a continuous search for newer sedative agents. Dexmedetomidine is a newer sedative agent for provision of short-term sedation (<24 h) in adult patients in the intensive care unit setting. It is a selective α2 adrenergic receptor agonist. The reports on off-label use of this drug in a variety of settings for invasive and non invasive procedural sedation have provided encouraging results. MATERIAL AND

methodsThe present paper reports a pilot study observing clinical efficacy of the newer drug dexmedetomidine in patients undergoing office based sliding genioplasty for correction of facial asymmetry. Subjects were sedated with dexmedetomidine with a loading dose of 0.5 mcg/kg over 10 min followed by a continuous infusion dose of 0.1 mcg/kg/h, the recovery process was observed for 60 min after the dexmedetomidine infusion was stopped. The patients were observed pre operatively, intra operatively (every 10 min) and postoperatively for the following parameters-oxygen saturation (SpO2), mean arterial pressure (MAP), heart rate (HR), and Ramsay sedation score (RSS), respiratory rate, pain scale.

Indexed as

DexmedetomidineGenioplastyLocal anaesthesiaOffice basedSedation

Identifiers

PMID26225072
PMCPMC4511891

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.