ArticleJournal of maxillofacial and oral surgery2014
Comparative, Histological and Histomorphometric Analysis of Three Anorganic Bovine Xenogenous Bone Substitutes: Bio-Oss, Bone-Fill and Gen-Ox Anorganic.
Article in Journal of maxillofacial and oral surgery, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed.
- Standardized Photobiomodulation Dosimetry Targeting the Base of Calvarial Critical-Sized Defects for Bone Regeneration: A Preclinical RCT Comparing Flattop vs. Gaussian Beam Profiles, with or Without Bio-OssJournal of functional biomaterials · 2026Article
- Optimization of Calcined Bone Powder and Silane-Crosslinked Alginate Composites for Enhanced Mechanical Performance as a Cortical Bone Substitute.Annals of biomedical engineering · 2026Article
- Comparison of bone regeneration in rabbit calvarial defects following the use of two different xenografts with a barrier membrane: A histological, histomorphometric, and micro-computed tomography study.Dental research journal · 2026Article
- Xenograft-Induced Damage and Synechiae Formation in the Maxillary Sinus Mucosa: A Retrospective Histological Analysis in Rabbits.Dentistry journal · 2025Article
- Impact of Collagenated and Non-Collagenated Deproteinized Bovine Bone Mineral on Schneiderian Membrane Integrity in Rabbits.Dentistry journal · 2025Article
- Sequential Bone Repair in Rabbit Sinus Lifts Using Bio-Oss and Hyaluronic Acid-Polynucleotide Gel (Regenfast).Journal of functional biomaterials · 2024Article
- A comparative analysis of particulate bovine bone substitutes for oral regeneration: a narrative review.International journal of implant dentistry · 2024Review
- Photobiomodulation Therapy Improves Repair of Bone Defects Filled by Inorganic Bone Matrix and Fibrin Heterologous Biopolymer.Bioengineering (Basel, Switzerland) · 2024Article
- Evaluation of Two Anorganic Bovine Xenogenous Grafts in Bone Healing of Critical Defect in Rats Calvaria.Brazilian dental journal · 2024Article
- Regeneration of Buccal Wall Defects after Tooth Extraction with Biphasic Calcium Phosphate in Injectable Form vs. Bovine Xenograft: A Randomized Controlled Clinical Trial.Dentistry journal · 2023Article
- The Interplay of Raloxifene and Sonochemical Bio-Oss in Early Maxillary Sinus Bone Regeneration: A Histological and Immunohistochemical Analysis in Rabbits.Medicina (Kaunas, Lithuania) · 2023Article
- Use of Photobiomodulation Combined with Fibrin Sealant and Bone Substitute Improving the Bone Repair of Critical Defects.Polymers · 2022Article
- Comparison of Two Bovine Commercial Xenografts in the Regeneration of Critical Cranial Defects.Molecules (Basel, Switzerland) · 2022Article
- Biological Behavior of Xenogenic Scaffolds in Alcohol-Induced Rats: Histomorphometric and Picrosirius Red Staining Analysis.Polymers · 2022Article
- CSBD Healing in Rats after Application of Bovine Xenogeneic Biomaterial Enriched with Magnesium Alloy.International journal of molecular sciences · 2021Article
- SEM-EDX Study of the Degradation Process of Two Xenograft Materials Used in Sinus Lift Procedures.Materials (Basel, Switzerland) · 2017Article
- Emerging Perspectives in Scaffold for Tissue Engineering in Oral Surgery.Stem cells international · 2017Review
- Bone defect rehabilitation using lyophilized bone preshaped on a stereolithographic model.Contemporary clinical dentistryArticle
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionAnorganic bovine xenogenous grafts show the best performance as bone substitutes in implantodontics. Bio-Oss is the world's most widely used and investigated anorganic bone substitute. This article compares two anorganic bovine bone substitutes (Bone-Fill and Gen-Ox anorganic) with Bio-Oss. MATERIALS AND
methodsEight New Zealand rabbits were implanted with 4 titanium cylinders randomly filled with Bio-Oss, Bone-Fill, Gen-Ox anorganic or a blood clot. Four animals were sacrificed after 8 weeks; 12 weeks later, the remaining four were sacrificed. The contents of the cylinders were removed, cut and stained with HE before they were evaluated with an optical microscope. The samples were submitted to histomorphometry for analysis.
resultsThe bone formation with Bio-Oss at 8 weeks was 8.43 mm(2); at 12 weeks, it was 9.32 mm(2). The bone formation with Bone-Fill at 8 weeks was 7.24 mm(2); at 12 weeks, it was 9.01 mm(2). The bone formation with Gen-Ox anorganic at 8 weeks was 2.78 mm(2); at 12 weeks, it was 3.02 mm(2). The bone formation with the blood clot at 8 weeks was 0.65 mm(2); at 12 weeks, it was 0.63 mm(2).
conclusionFollowing this model, Bone-Fill was comparable to Bio-Oss and superior to Gen-Ox and blood clot.
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Registered trials
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