Evidence map›Paper›PMID 26224874›Full record

ArticleClinical cancer research : an official journal of the American Association for Cancer Research2015

Imaging Tumor Acidity: pH-Low Insertion Peptide Probe for Optoacoustic Tomography.

Yana K Reshetnyak

Open access · greenAbstract readComment
In one paragraph

Article in Clinical cancer research : an official journal of the American Association for Cancer Research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 35 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Article
  8. Multiplexed imaging in oncology.Nature biomedical engineering · 2022
    Review
  9. Article
  10. Article
  11. Toxic proteins application in cancer therapy.Molecular biology reports · 2021
    Review
  12. Article
  13. Advances on Tumor-Targeting Delivery of Cytotoxic Proteins.ACS pharmacology & translational science · 2020
    Review
  14. Article
  15. Article
  16. Review
  17. Article
  18. Current and Emerging Clinical Applications of Multispectral Optoacoustic Tomography (MSOT) in Oncology.Clinical cancer research : an official journal of the American Association for Cancer Research · 2016
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Yana K ReshetnyakDivision Biological and Medical Physics, Physics Department, University of Rhode Island, Kingston, Rhode Island. reshetnyak@uri.edu.
University of Rhode Island · US

Funding

TM INTERACTIONS IN MEMBRANE PROTEIN FOLDING AND FUNCTIONR01GM073857 · NIGMS · YALE UNIVERSITY · PI ANDREEV, OLEG A, ENGELMAN, DONALD M. · 2006 to 2023
$8.4M
Mapping pH at the surface of individual cellR21CA174413 · NCI · UNIVERSITY OF RHODE ISLAND · PI ANDREEV, OLEG A, RESHETNYAK, YANA K · 2012 to 2013
$415k
NCI NIH HHS CA174413NCI NIH HHS R21 CA174413NIGMS NIH HHS GM073857NIGMS NIH HHS R01 GM073857
6 · The paper itself

Abstract

Optoacoustic tomography has been used for the detection of pancreatic ductal adenocarcinoma targeted by pH-low insertion peptide (pHLIP) conjugated to near-infrared fluorescent dye. It was proved that tumor targeting is pH dependent. The approach could have major implication for detection and monitoring of pancreatic and other cancers.

Indexed as

AdenocarcinomaAnimalsFemaleHumansMembrane ProteinsPancreatic NeoplasmsMembrane Proteins

Identifiers

PMID26224874
PMCPMC4609264
OpenAlexW2109473282

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.