ArticleJournal of neurophysiology2015
Distinct dynamics of ramping activity in the frontal cortex and caudate nucleus in monkeys.
Article in Journal of neurophysiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
17 citing papers in PubMed.
- Distinct involvements of the subthalamic nucleus subpopulations in reward-biased decision-making in monkeys.eLife · 2026Article
- Visual Simulation Is Supported by Sequential Monitoring in the Lateral Prefrontal Cortex.Journal of cognitive neuroscience · 2026Article
- Distinct involvements of the subthalamic nucleus subpopulations in reward-biased decision-making in monkeys.bioRxiv : the preprint server for biology · 2025Article
- Article
- Distinct neural population code and causal roles of primate caudate nucleus in multimodal decision-making.Nature communications · 2025Article
- Neural Representations of Post-Decision Accuracy and Reward Expectation in the Caudate Nucleus and Frontal Eye Field.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Contributions of the Basal Ganglia to Visual Perceptual Decisions.Annual review of vision science · 2023Review
- Variable Statistical Structure of Neuronal Spike Trains in Monkey Superior Colliculus.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021Article
- Frontal eye field and caudate neurons make different contributions to reward-biased perceptual decisions.eLife · 2020Article
- Article
- Causal contribution and dynamical encoding in the striatum during evidence accumulation.eLife · 2018Article
- Coordinated Ramping of Dorsal Striatal Pathways preceding Food Approach and Consumption.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2018Article
- Dynamic Flexibility in Striatal-Cortical Circuits Supports Reinforcement Learning.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2018Article
- Functional dissection of signal and noise in MT and LIP during decision-making.Nature neuroscience · 2017Article
- Posterior Parietal Cortex Guides Visual Decisions in Rats.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2017Article
- Parsing Heterogeneous Striatal Activity.Frontiers in neuroanatomy · 2017Review
- Decision Making and Sequential Sampling from Memory.Neuron · 2016Review
Corrections and comments
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Authors and funding
1 author.
Funding
Abstract
The prefronto-striatal network is involved in many cognitive functions, including perceptual decision making and reward-modulated behaviors. For well-trained subjects, neural responses frequently show similar patterns in the prefrontal cortex and striatum, making it difficult to tease apart distinct regional contributions. Here I show that, despite similar mean firing rate patterns, prefrontal and striatal responses differ in other temporal dynamics for both perceptual and reward-based tasks. Compared with simulation results, the temporal dynamics of prefrontal activity are consistent with an accumulation of sensory evidence used to solve a perceptual task but not with an accumulation of reward context-related information used for the development of a reward bias. In contrast, the dynamics of striatal activity is consistent with an accumulation of reward context-related information and with an accumulation of sensory evidence during early stimulus viewing. These results suggest that prefrontal and striatal neurons may have specialized functions for different tasks even with similar average activity.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.