Evidence map›Paper›PMID 26224611›Full record

Observational studyInternational orthopaedics2016

One-stage revision of infected hip arthroplasty: outcome of 39 consecutive hips.

Thomas Ilchmann, Werner Zimmerli, Peter Emil Ochsner, Bernhard Kessler, Lukas Zwicky, Peter Graber, Martin Clauss

Open access · hybridAbstract readObservational Study
PubMed Publisher
In one paragraph

Observational study in International orthopaedics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 5 pooled it
8.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 5 syntheses or guidelines pooled it, 81 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Survivorship and Etiologies of Failure in Single-stage Revision Arthroplasty for Periprosthetic Joint Infection: A Meta-analysis.Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews · 2023
    Pooled it
  4. Pooled it
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  6. Article
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  9. Review
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  11. Review
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  13. Article
  14. Observational
  15. Review
  16. Article
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  19. The Impact of Surgical Strategy and Rifampin on Treatment Outcome in Cutibacterium Periprosthetic Joint Infections.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2021
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Thomas IlchmannHirslanden Klink Birshof, Münchenstein, Switzerland. thomas.ilchmann@hirslanden.ch.
Werner ZimmerliInterdisciplinary Unit for Orthopaedic Infections and Basel University Medical Clinic, Kantonsspital Baselland Liestal, Liestal, Switzerland.
Peter Emil OchsnerInterdisciplinary Unit for Orthopaedic Infections and Clinic for Orthopaedics and Trauma Surgery, Kantonsspital Baselland Liestal, Liestal, Switzerland.
Bernhard KesslerInterdisciplinary Unit for Orthopaedic Infections and Basel University Medical Clinic, Kantonsspital Baselland Liestal, Liestal, Switzerland.
Lukas ZwickyClinic for Orthopaedics and Trauma Surgery, Kantonsspital Baselland Liestal, Liestal, Switzerland.
Peter GraberInterdisciplinary Unit for Orthopaedic Infections and Basel University Medical Clinic, Kantonsspital Baselland Liestal, Liestal, Switzerland.
Martin ClaussInterdisciplinary Unit for Orthopaedic Infections and Clinic for Orthopaedics and Trauma Surgery, Kantonsspital Baselland Liestal, Liestal, Switzerland.
Kantonsspital Baselland · CHHirslanden Klinik Birshof · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThere are various options for treating periprosthetic joint infection (PJI). Two-stage exchange has traditionally been the gold standard. However, if the appropriate surgical intervention is chosen according to a rational algorithm, the outcome is similar when using all types of interventions. In an observational cohort study, the outcome of patients with PJI after hip replacement treated with one-stage revision was analysed.

methodsAll patients fulfilling all criteria for one-stage exchange according to the Infectious Diseases Society of America (IDSA) guidelines and six without preoperative identification of a microorganism were included. Implant removal, debridement and cemented or uncemented reimplantations were performed in a single intervention. If a cemented device was implanted, commercially available gentamicin cement was used in all cases. Antibiotic treatment was administered intravenously for at least 2 weeks, followed by oral therapy for a total duration of 3 months. Patients had standardised clinical and radiological follow-up visits.

resultsBetween 1996 and 2011, 38 patients (39 hips) were treated with a one-stage procedure and followed for at least 2 years. Coagulase-negative staphylococci were the most frequent pathogens, and polymicrobial infection was observed in five cases. In 25 hips, an uncemented revision stem was implanted, and 37 hips received an acetabular reinforcement ring. The mean follow-up was 6.6 (2.0-15.1) years. No patient had persistent, recurrent or new infection. There were four stem revisions for aseptic loosening. The mean Harris Hip Score was 81 points (26-99) at the final follow-up.

conclusionsExcellent cure rate and function seen in our study suggest that one-stage exchange is a safe procedure, even without local antibiotic treatment, provided that the patient has no sinus tract or severe soft tissue damage, no major bone grafting is required and the microorganism is susceptible to orally administered agents with high bioavailability.

Indexed as

AgedAnti-Bacterial AgentsArthroplasty, Replacement, HipCohort StudiesDebridementFemaleFollow-Up StudiesHipHip JointHip ProsthesisHumansMaleMiddle AgedProsthesis-Related InfectionsReoperationTreatment OutcomeAnti-Bacterial AgentsHip arthroplastyHip replacementInfectionOne-stageTreatmentUncemented

Identifiers

PMID26224611
OpenAlexW959594608

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.