Evidence map›Paper›PMID 26224573›Full record

ArticleInternational journal of impotence research

Predicting erectile dysfunction in sexually active patients seeking prostate health screening: proposal for a multivariable risk stratification.

V Favilla, G I Russo, G Reale, S Leone, T Castelli, S La Vignera, R A Condorelli, A E Calogero, S Cimino, G Morgia

Abstract read
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In one paragraph

Article in International journal of impotence research. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

V FavillaDepartment of Urology, University of Catania, Catania, Italy.
G I RussoDepartment of Urology, University of Catania, Catania, Italy.
G RealeDepartment of Urology, University of Catania, Catania, Italy.
S LeoneDepartment of Urology, University of Catania, Catania, Italy.
T CastelliDepartment of Urology, University of Catania, Catania, Italy.
S La VigneraDepartment of Medical and Pediatric Sciences, Section of Endocrinology, Andrology, and Internal Medicine, University of Catania, Catania, Italy.
R A CondorelliDepartment of Medical and Pediatric Sciences, Section of Endocrinology, Andrology, and Internal Medicine, University of Catania, Catania, Italy.
A E CalogeroDepartment of Medical and Pediatric Sciences, Section of Endocrinology, Andrology, and Internal Medicine, University of Catania, Catania, Italy.
S CiminoDepartment of Urology, University of Catania, Catania, Italy.
G MorgiaDepartment of Urology, University of Catania, Catania, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To address the severity of erectile dysfunction (ED) in consecutive sexually active men seeking a prostate health screening through a multivariable risk stratification including comorbidities and lower urinary tract symptoms (LUTS). Four hundred and twenty five consecutive subjects with stable sexual relationship with normal testosterone levels were enrolled. The International Index of Erectile Function (IIEF-5) and the International Prostate Symptom Score (IPSS) questionnaires were collected and health-significant comorbidities were scored with the Charlson comorbidity index (CCI). All the independent predictors of ED were combined to form four different risk categories of ED: low (age⩽65 years and IPSS<8 and CCI=0), intermediate (one of the following: age>65 years, IPSS⩾8 or CCI⩾1), high (two of the following: age>65 years, IPSS⩾8 or CCI⩾1) and very high (age >65 years, IPSS⩾8 and CCI⩾1). The prevalence of ED increased with increase of CCI (χ(2) likelihood ratio: 40.85, P=0.001). The median of the IIEF-5 significantly reduced with the increase of the CCI (P<0.001) and with the worsening of our risk group stratification (P<0.001). At univariate logistic regression analysis very high risk was significantly associated with of ED (odds ratio: 26.85, P<0.001). Very high-risk group predicted ED with 88% and 56% of specificity and sensitivity, respectively. Combining these risk factors through our risk stratification may be usefulness in revealing an underling ED.

Indexed as

ProstateReproductive HealthAgedDiabetes MellitusErectile DysfunctionHumansHyperlipidemiasHypertensionLower Urinary Tract SymptomsMaleMiddle AgedMyocardial InfarctionOdds RatioRisk FactorsSurveys and QuestionnairesTestosteroneTestosterone

Identifiers

PMID26224573

What OpenQuestion holds

Textmetadata
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.