Evidence map›Paper›PMID 26224434›Full record

ArticleJournal of the American Association for Laboratory Animal Science : JAALAS2015

Hematology and Clinical Chemistry Measures During and After Pregnancy and Age- and Sex-Specific Reference Intervals in African Green Monkeys (Chlorocebus aethiops sabaeus).

Lee Chichester, Melaney K Gee, Matthew J Jorgensen, Jay R Kaplan

Open access · greenAbstract read
In one paragraph

Article in Journal of the American Association for Laboratory Animal Science : JAALAS, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.7field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 41 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Factors Affecting Hematologic and Serum Biochemical Parameters in Healthy Common Marmosets (Journal of the American Association for Laboratory Animal Science : JAALAS · 2022
    Article
  6. Species Differences in Tryptophan Metabolism and Disposition.International journal of tryptophan research : IJTR · 2022
    Review
  7. Age-Related Colonic Mucosal Microbiome Community Shifts in Monkeys.The journals of gerontology. Series A, Biological sciences and medical sciences · 2021
    Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Lee ChichesterUniversity of Washington, Washington National Primate Research Center, Seattle, Washington, USA.
Melaney K GeeWake Forest University, Animal Resources Program, Winston-Salem, North Carolina, USA; Wake Forest School of Medicine, Department of Pathology, Section on Comparative Medicine, Winston-Salem, North Carolina, USA.
Matthew J JorgensenWake Forest School of Medicine, Department of Pathology, Section on Comparative Medicine, Winston-Salem, North Carolina, USA. mjorgens@wakehealth.edu.
Jay R KaplanWake Forest School of Medicine, Department of Pathology, Section on Comparative Medicine, Winston-Salem, North Carolina, USA.
University of Washington · US

Funding

Vervet Research Colony as a Biomedical ResourceP40OD010965 · OD · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI Matthew Jorgensen · 2012 to 2026
$14.6M
NIH HHS OD010965NIH HHS P40 OD010965
6 · The paper itself

Abstract

Clinical decisions and experimental analyses often involve the assessment of hematology and clinical chemistry. Using clinical pathology to assess the health status of NHP in breeding colonies or data from studies than involve pregnancy can often be complicated by pregnancy status. This study had 2 objectives regarding the hematology and clinical chemistry of African green monkeys (AGM, Chlorocebus aethiops sabaeus): 1) to compare pregnant or recently postpartum animals with nonpregnant, nonlactating animals and 2) to create age- and sex-specific reference intervals. Subjects in this study were 491 AGM from the Vervet Research Colony of the Wake Forest University Primate Center. Results indicated that changes in BUN, serum total protein, albumin, ALP, GGT, calcium, phosphorus, sodium, potassium, cholesterol, total CO2, globulins, lipase, amylase, WBC, neutrophils, lymphocytes, platelets, RBC, Hgb, and Hct occur during pregnancy and the postpartum period. Age- and sex-specific reference intervals consistent with guidelines from the American Society for Veterinary Clinical Pathology were established and further expand the understanding of how to define health in AGM on the basis of clinical pathology. The combination of understanding the changes that occur in pregnancy and postpartum and expansive reference intervals will help guide clinical and experimental decisions.

Indexed as

AnimalsChlorocebus aethiopsFemaleHematologic TestsMaleNeutrophilsPostpartum PeriodPregnancyReference ValuesSex Characteristics

Identifiers

PMID26224434
PMCPMC4521568
OpenAlexW2399495384

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.