Evidence map›Paper›PMID 26224363›Full record

ArticleJournal of bone and mineral metabolism2016

The association between vitamin D and parathyroid hormone and bone mineral density: the Dong-gu Study.

Seong-Woo Choi, Sun-Seog Kweon, Jin-Su Choi, Jung-Ae Rhee, Young-Hoon Lee, Hae-Sung Nam, Seul-Ki Jeong, Kyeong-Soo Park, So-Yeon Ryu, Hye-Rim Song and 1 more

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In one paragraph

Article in Journal of bone and mineral metabolism, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.2field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

  1. Effect of vitamin DJournal of the International Society of Sports Nutrition · 2023
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  7. Characteristics of incidence hip fracture cases in older adults participating in the longitudinal AGES-Reykjavik study.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2021
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 7 institutions in 1 country.

Seong-Woo ChoiDepartment of Preventive Medicine, Chosun University Medical School, 309, Pilmun-daero, Dong-gu, Gwangju, 501-759, Republic of Korea.
Sun-Seog KweonDepartment of Preventive Medicine, Chonnam National University Medical School, 160 Baekseo-ro, Dong-gu, Gwangju, 501-746, Republic of Korea.
Jin-Su ChoiDepartment of Preventive Medicine, Chonnam National University Medical School, 160 Baekseo-ro, Dong-gu, Gwangju, 501-746, Republic of Korea.
Jung-Ae RheeDepartment of Preventive Medicine, Chonnam National University Medical School, 160 Baekseo-ro, Dong-gu, Gwangju, 501-746, Republic of Korea.
Young-Hoon LeeDepartment of Preventive Medicine and Institute of Wonkwang Medical Science, Wonkwang University School of Medicine, 344-2 Shinyong-dong, Iksan, Jeollabukdo, 570-711, Republic of Korea.
Hae-Sung NamDepartment of Preventive Medicine, Chungnam National University Medical School, Munhwa 1(il)-dong, Jung-gu, Daejeon, 301-747, Republic of Korea.
Seul-Ki JeongDepartment of Neurology and Research Institute of Clinical Medicine, Chobuk National University-Biomedical Institute of Chonbuk National University Hospital, San 2-20, Geumam-dong, Deokjin-gu, Jeonju, Jeollabukdo, 561-180, Republic of Korea.
Kyeong-Soo ParkDepartment of Preventive Medicine, Seonam University College of Medicine, Namwon, Republic of Korea.
So-Yeon RyuDepartment of Preventive Medicine, Chosun University Medical School, 309, Pilmun-daero, Dong-gu, Gwangju, 501-759, Republic of Korea.
Hye-Rim SongDepartment of Laboratory Medicine, Chonnam National University Hwasun Hospital, 322 Seoyang-ro, Hwasun, Jeollanamdo, 519-809, Republic of Korea.
Min-Ho ShinDepartment of Preventive Medicine, Chonnam National University Medical School, 160 Baekseo-ro, Dong-gu, Gwangju, 501-746, Republic of Korea. mhshinx@paran.com.
Chonnam National University · KRChosun University · KRChonnam National University Hwasun Hospital · KRChungnam National University · KRJeonbuk National University Hospital · KRSeonam University · KRWonkwang University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The primary objective of the present study was to investigate the relationship between 25-hydroxyvitamin D (25[OH]D) and areal bone mineral density (aBMD) in Korean subjects from the general population aged ≥50 years. This study included 8,857 individuals who completed the baseline survey of the Dong-gu study, which was conducted in Korea from 2007-2010. The participants who fulfilled the detailed inclusion criteria underwent assessment of the femoral neck and lumbar spine aBMD as well as measurement of serum 25(OH)D and parathyroid hormone (PTH) levels. After adjusting for other covariates and log-PTH values, the mean aBMD of the femoral neck exhibited a significant increase with increasing 25(OH)D levels in both males (p < 0.001) and females (p = 0.005). Additionally, the mean aBMD of the lumbar spine exhibited a significant increase with increasing 25(OH)D levels in males (p = 0.011) but not females (p = 0.252). After adjusting for covariates and log-25(OH)D values, the mean aBMD values of the femoral neck and lumbar spine showed significant decreases with increasing PTH levels in both males and females (p < 0.001). The present findings demonstrate that the aBMD of the femoral neck was significantly associated with 25(OH)D levels independent of PTH in both males and females and that the aBMD of the lumbar spine was significantly associated with 25(OH)D levels independent of PTH in males, but not females.

Indexed as

Bone DensityAgedFemaleFemur NeckHumansLumbar VertebraeMaleMiddle AgedParathyroid HormoneProspective StudiesRepublic of KoreaVitamin D25-hydroxyvitamin DParathyroid HormoneVitamin DBone mineral densityParathyroid hormoneVitamin D

Identifiers

PMID26224363
OpenAlexW1035040832

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.