Evidence map›Paper›PMID 26223881›Full record

ReviewMammalian genome : official journal of the International Mammalian Genome Society2015

Orthology for comparative genomics in the mouse genome database.

Mary E Dolan, Richard M Baldarelli, Susan M Bello, Li Ni, Monica S McAndrews, Carol J Bult, James A Kadin, Joel E Richardson, Martin Ringwald, Janan T Eppig and 1 more

Abstract readComparative StudyHistorical ArticleReview
In one paragraph

Review in Mammalian genome : official journal of the International Mammalian Genome Society, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Review
  6. Mouse genome database 2016.Nucleic acids research · 2016
    Article
  7. Mouse Genome Informatics (MGI): reflecting on 25 years.Mammalian genome : official journal of the International Mammalian Genome Society · 2015
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Mary E DolanThe Jackson Laboratory, Bar Harbor, ME, 04609, USA, mary.dolan@jax.org.
Richard M Baldarelli
Susan M Bello
Li Ni
Monica S McAndrews
Carol J Bult
James A Kadin
Joel E Richardson
Martin Ringwald
Janan T Eppig
Judith A Blake

Funding

SOFTWARE AND DATABASE SYSTEM DEVELOPMENTP41HG000330 · NHGRI · JACKSON LABORATORY · PI EPPIG, JANAN T. · 1995 to 2010
$72.1M
Shared Resource ManagementP30CA034196 · NCI · JACKSON LABORATORY · PI Jeffrey Hsu-Min Chuang · 1985 to 2026
$61.9M
Mouse Genome DatabaseU41HG000330 · NHGRI · JACKSON LABORATORY · PI BLAKE, JUDITH A, BULT, CAROL J · 2011 to 2020
$45.5M
Technical DevelopmentP41HD062499 · NICHD · JACKSON LABORATORY · PI MARTIN RINGWALD · 2011 to 2026
$37.3M
Resource ProjectU41HG002273 · NHGRI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI THOMAS, PAUL D. · 2012 to 2021
$34.7M
Gene Ontology ConsortiumP41HG002273 · NHGRI · JACKSON LABORATORY · PI BLAKE, JUDITH A · 2004 to 2011
$27.4M
GENE ONTOLOGY CONSORTIUMR01HG002273 · NHGRI · JACKSON LABORATORY · PI BLAKE, JUDITH A · 2001 to 2003
$5.8M
MULTI-LEVEL ANALYSIS AND DISPLAY OF MOUSE GENOME DATAP01HG000330 · NHGRI · JACKSON LABORATORY · PI EPPIG, JANAN T. · 1990 to 1994
–
NCI NIH HHS P30 CA034196NHGRI NIH HHS HG000330NHGRI NIH HHS HG002273NHGRI NIH HHS P41 HG000330NHGRI NIH HHS P41 HG002273NHGRI NIH HHS R01 HG002273NHGRI NIH HHS U41 HG000330NHGRI NIH HHS U41 HG002273NICHD NIH HHS HD062499NICHD NIH HHS P41 HD062499
6 · The paper itself

Abstract

The mouse genome database (MGD) is the model organism database component of the mouse genome informatics system at The Jackson Laboratory. MGD is the international data resource for the laboratory mouse and facilitates the use of mice in the study of human health and disease. Since its beginnings, MGD has included comparative genomics data with a particular focus on human-mouse orthology, an essential component of the use of mouse as a model organism. Over the past 25 years, novel algorithms and addition of orthologs from other model organisms have enriched comparative genomics in MGD data, extending the use of orthology data to support the laboratory mouse as a model of human biology. Here, we describe current comparative data in MGD and review the history and refinement of orthology representation in this resource.

Indexed as

GenomeSequence Homology, Amino AcidAllelesAnimalsDatabases, GeneticDisease Models, AnimalGenomicsGenotypeHistory, 20th CenturyHistory, 21st CenturyHumansMiceMolecular Sequence AnnotationPhenotypePhylogeny

Identifiers

PMID26223881
PMCPMC4534493

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.