Evidence map›Paper›PMID 26223794›Full record

ArticleAngewandte Chemie (International ed. in English)2015

Semiconducting Polymer Nanoparticles with Persistent Near-Infrared Luminescence for In Vivo Optical Imaging.

Mikael Palner, Kanyi Pu, Shirley Shao, Jianghong Rao

Abstract read
In one paragraph

Article in Angewandte Chemie (International ed. in English), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
11.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 201 citations in OpenAlex.

  1. Review
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  8. Continuous Condensed Triplet Accumulation for Irradiance-Induced Anticounterfeit Afterglow.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023
    Article
  9. Luminescence Thermometry with Nanoparticles: A Review.Nanomaterials (Basel, Switzerland) · 2023
    Review
  10. Article
  11. Review
  12. Review
  13. Review
  14. Article
  15. Article
  16. Article
  17. Review
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  19. HNature communications · 2020
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 2 countries.

Mikael PalnerDepartment of Radiology, Molecular Imaging Program at Stanford, Stanford University School of Medicine, Stanford, CA 94395-5484 (USA) http://www.raolab.stanford.edu.
Kanyi PuDepartment of Radiology, Molecular Imaging Program at Stanford, Stanford University School of Medicine, Stanford, CA 94395-5484 (USA) http://www.raolab.stanford.edu.
Shirley ShaoDepartment of Radiology, Molecular Imaging Program at Stanford, Stanford University School of Medicine, Stanford, CA 94395-5484 (USA) http://www.raolab.stanford.edu.
Jianghong RaoDepartment of Radiology, Molecular Imaging Program at Stanford, Stanford University School of Medicine, Stanford, CA 94395-5484 (USA) http://www.raolab.stanford.edu. jrao@stanford.edu.
Stanford University · US

Funding

Nanoprobes for imaging RONS and drug-induced hepatotoxicityR01DK099800 · NIDDK · STANFORD UNIVERSITY · PI RAO, JIANGHONG · 2013 to 2016
$1.4M
NIDDK NIH HHS R01 DK099800NIDDK NIH HHS R01DK099800
6 · The paper itself

Abstract

Materials with persistent luminescence are attractive for in vivo optical imaging since they have a long lifetime that allows the separation of excitation of fluorophores and image acquisition for time-delay imaging, thus eliminating tissue autofluorescence associated with fluorescence imaging. Persistently luminescent nanoparticles have previously been fabricated from toxic rare-earth metals. This work reports that nanoparticles made of the conjugated polymer MEH-PPV can generate luminescence persisting for an hour upon single excitation. A near-infrared dye was encapsulated in the conjugated polymer nanoparticle to successfully generate persistent near-infrared luminescence through resonance energy transfer. This new persistent luminescence nanoparticles have been demonstrated for optical imaging applications in living mice.

Indexed as

NanoparticlesSemiconductorsSpectroscopy, Near-InfraredAnimalsLuminescenceMicePolymersPolymersfluorescencein vivo imagingMEH-PPVpersistent luminescencepolymer nanoparticle

Identifiers

PMID26223794
PMCPMC4575640
OpenAlexW2108579748

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.