Evidence map›Paper›PMID 26223474›Full record

ArticleScientific reports2015

Exploring bubble oscillation and mass transfer enhancement in acoustic-assisted liquid-liquid extraction with a microfluidic device.

Yuliang Xie, Chandraprakash Chindam, Nitesh Nama, Shikuan Yang, Mengqian Lu, Yanhui Zhao, John D Mai, Francesco Costanzo, Tony Jun Huang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.0field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 47 citations in OpenAlex.

  1. Article
  2. Article
  3. Periodic Flows in Microfluidics.Small (Weinheim an der Bergstrasse, Germany) · 2024
    Review
  4. Article
  5. Article
  6. Review
  7. Review
  8. Probing Cell Deformability via Acoustically Actuated Bubbles.Small (Weinheim an der Bergstrasse, Germany) · 2016
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Yuliang Xie1] Department of Chemical Engineering, The Pennsylvania State University, University Park, Pennsylvania 16802, USA [2] Department of Engineering Science and Mechanics, The Pennsylvania State University, University Park, PA 16802, USA.
Chandraprakash ChindamDepartment of Engineering Science and Mechanics, The Pennsylvania State University, University Park, PA 16802, USA.
Nitesh NamaDepartment of Engineering Science and Mechanics, The Pennsylvania State University, University Park, PA 16802, USA.
Shikuan YangDepartment of Engineering Science and Mechanics, The Pennsylvania State University, University Park, PA 16802, USA.
Mengqian LuDepartment of Engineering Science and Mechanics, The Pennsylvania State University, University Park, PA 16802, USA.
Yanhui ZhaoDepartment of Engineering Science and Mechanics, The Pennsylvania State University, University Park, PA 16802, USA.
John D MaiDepartment of Mechanical and Biomedical Engineering, City University of Hong Kong, Tat Chee Avenue, Kowloon, Hong Kong SAR.
Francesco Costanzo1] Department of Engineering Science and Mechanics, The Pennsylvania State University, University Park, PA 16802, USA [2] Center for Neural Engineering, The Pennsylvania State University, University Park, PA 16802, USA.
Tony Jun Huang1] Department of Chemical Engineering, The Pennsylvania State University, University Park, Pennsylvania 16802, USA [2] Department of Engineering Science and Mechanics, The Pennsylvania State University, University Park, PA 16802, USA [3] Department of Biomedical Engineering, The Pennsylvania State University, University Park, PA 16802, USA.
Pennsylvania State University · USCity University of Hong Kong · HK

Funding

Standing Surface Acoustic Wave Based Cell Sorters for Maintaining Cell IntegrityR01GM112048 · NIGMS · PENNSYLVANIA STATE UNIVERSITY, THE · PI HUANG, TONY JUN · 2014 to 2017
$1.1M
Validation of acoustic tweezers for single-cell analyses of purine metabolismR33EB019785 · NIBIB · PENNSYLVANIA STATE UNIVERSITY, THE · PI HUANG, TONY JUN · 2014 to 2016
$1.1M
NIBIB NIH HHS 1R33EB019785-01NIBIB NIH HHS R33 EB019785NIGMS NIH HHS 1 R01 GM112048-01A1NIGMS NIH HHS R01 GM112048
6 · The paper itself

Abstract

We investigated bubble oscillation and its induced enhancement of mass transfer in a liquid-liquid extraction process with an acoustically-driven, bubble-based microfluidic device. The oscillation of individually trapped bubbles, of known sizes, in microchannels was studied at both a fixed frequency, and over a range of frequencies. Resonant frequencies were analytically identified and were found to be in agreement with the experimental observations. The acoustic streaming induced by the bubble oscillation was identified as the cause of this enhanced extraction. Experiments extracting Rhodanmine B from an aqueous phase (DI water) to an organic phase (1-octanol) were performed to determine the relationship between extraction efficiency and applied acoustic power. The enhanced efficiency in mass transport via these acoustic-energy-assisted processes was confirmed by comparisons against a pure diffusion-based process.

Indexed as

1-OctanolAcousticsAlgorithmsDiffusionLiquid-Liquid ExtractionMicrofluidic Analytical TechniquesRhodaminesWater1-Octanolrhodamine BRhodaminesWater

Identifiers

PMID26223474
PMCPMC4519785
OpenAlexW1041813934

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.