Trial reportMedicine2015
Risk Models of Operative Morbidities in 16,930 Critically Ill Surgical Patients Based on a Japanese Nationwide Database.
Trial report in Medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 20 citations in OpenAlex.
- Annual Report of the 2022 National Clinical Database: Decade-Long Trends and Current Status of Gastroenterological Surgery in Japan.Annals of gastroenterological surgery · 2026Article
- Which Method Best Predicts Postoperative Complications: Deep Learning, Machine Learning, or Conventional Logistic Regression?Annals of gastroenterological surgery · 2026Review
- Annual report on National Clinical Database 2021 for gastroenterological surgery in Japan.Annals of gastroenterological surgery · 2025Article
- Intestinal dysbiosis as an intraoperative predictor of septic complications: evidence from human surgical cohorts and preclinical models of peritoneal sepsis.Scientific reports · 2023Article
- Annual report on National Clinical Database 2020 for gastroenterological surgery in Japan.Annals of gastroenterological surgery · 2023Article
- Surgical outcomes in gastroenterological surgery in Japan: Report of the National Clinical Database 2011-2019.Annals of gastroenterological surgery · 2021Article
- Profiles of institutional departments affect operative outcomes of eight gastroenterological procedures.Annals of gastroenterological surgery · 2021Article
- Development of gastroenterological surgery over the last decade in Japan: analysis of the National Clinical Database.Surgery today · 2021Review
- Surgical outcomes in gastroenterological surgery in Japan: Report of the National Clinical Database 2011-2018.Annals of gastroenterological surgery · 2020Article
- Evaluating the quality of data from the Japanese National Clinical Database 2011 via a comparison with regional government report data and medical charts.Surgery today · 2019Article
- Risk assessment of morbidities after right hemicolectomy based on the National Clinical Database in Japan.Annals of gastroenterological surgery · 2018Article
- Surgical outcomes in gastroenterological surgery in Japan: Report of National Clinical database 2011-2016.Annals of gastroenterological surgery · 2018Article
- Association between the participation of board-certified surgeons in gastroenterological surgery and operative mortality after eight gastroenterological procedures.Surgery today · 2017Article
- Observational
- Therapeutic management of peritonitis: a comprehensive guide for intensivists.Intensive care medicine · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aim of the study was to evaluate preoperative variables predictive of lethal morbidities in critically ill surgical patients at a national level.There is no report of risk stratification for morbidities associated with mortality in critically ill patients with acute diffuse peritonitis (ADP).We examined data from 16,930 patients operated during 2011 and 2012 in 1546 different hospitals for ADP identified in the National Clinical Database of Japan. We analyzed morbidities significantly associated with operative mortality. Based on 80% of the population, we calculated independent predictors for these morbidities. The risk factors were validated using the remaining 20%.The operative mortality was 14.1%. Morbidity of any grade occurred in 40.2% of patients. Morbidities correlated with mortality, including septic shock, progressive renal insufficiency, prolonged ventilation >48 hours, systemic sepsis, central nervous system (CNS) morbidities, acute renal failure and pneumonia, and surgical site infection (SSI), were selected for risk models. A total of 18 to 29 preoperative variables were selected per morbidity and yielded excellent C-indices for each (septic shock: 0.851; progressive renal insufficiency: 0.878; prolonged ventilation >48 h: 0.849; systemic sepsis: 0.839; CNS morbidities: 0.848; acute renal failure: 0.868; pneumonia: 0.830; and SSI: 0.688).We report the first risk stratification study on lethal morbidities in critically ill patients with ADP using a nationwide surgical database. These risk models will contribute to patient counseling and help predict which patients require more aggressive surgical and novel pharmacological interventions.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.