Evidence map›Paper›PMID 26222158›Full record

Trial reportPloS one2015

Randomized Controlled Trial on the Effect of Channa striatus Extract on Measurement of the Uterus, Pulsatility Index, Resistive Index of Uterine Artery and Superficial Skin Wound Artery in Post Lower Segment Caesarean Section Women.

Mohd Rizal Abu Bakar, Azidah Abdul Kadir, Siti Zubaidah Abdul Wahab, Ahmad Helmy Abdul Karim, Nik Hazlina Nik Hussain, Norhayati Mohd Noor, Julia Omar, Saringat Bin Bai Bae, Wan Haslindawani Wan Mahmood, Asrenee Abdul Razak and 1 more

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Complementary and alternative therapies for post-caesarean pain.The Cochrane database of systematic reviews · 2020
    Pooled it
  2. Review
  3. Geriatrics (Basel, Switzerland) · 2024
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Mohd Rizal Abu BakarAdvanced Medical and Dental Institute, Universiti Sains Malaysia, Kubang Kerian, Malaysia.
Azidah Abdul KadirSchool of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian, Malaysia.
Siti Zubaidah Abdul WahabSchool of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian, Malaysia.
Ahmad Helmy Abdul KarimSchool of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian, Malaysia.
Nik Hazlina Nik HussainSchool of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian, Malaysia.
Norhayati Mohd NoorSchool of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian, Malaysia.
Julia OmarSchool of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian, Malaysia.
Saringat Bin Bai BaeSchool of Pharmaceutical Sciences, Universiti Sains Malaysia, Kubang Kerian, Malaysia.
Wan Haslindawani Wan MahmoodSchool of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian, Malaysia.
Asrenee Abdul RazakSchool of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian, Malaysia.
Rohaizan YunusInternational Medical University, Seremban, Malaysia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo compare the mean of anteroposterior (AP) measurements of the uterus in longitudinal and oblique transverse planes, and the pulsatility index (PI) and resistive index (RI) of the uterine artery and superficial skin wound artery between patients taking Channa striatus and placebo.

backgroundChanna striatus, also known as haruan, is a fresh water snakehead fish consumed in many parts of Southeast Asia. Channa striatus is also normally consumed by women postpartum to promote wound healing as well as to reduce post-operative pain. METHODOLOGY: This study is a randomised, double blind, placebo-controlled study conducted in women after Lower Segment Caesarean Section (LSCS). Subjects were randomised to either a Channa striatus or a placebo group and were given a daily dosage of 500 mg of Channa striatus extract or 500 mg maltodextrin, respectively, for six weeks post LSCS. The anteroposterior measurements of the uterus in the longitudinal and oblique transverse planes, and the pulsatility index (PI) and resistive index (RI) of the uterine and superficial skin wound arteries were assessed using pelvic Gray-scale ultrasound and Doppler ultrasound at baseline (Day 3) and at two weeks, four weeks and six weeks post-operatively.

resultsSixty-six subjects were randomised into the study with 33 in the Channa striatus group and 33 in the placebo group. No significant differences were detected in terms of the pulsatility index (PI) and the resistive index (RI) of the uterine and superficial skin wound arteries between the Channa striatus and placebo groups. However, in the Channa striatus group, the AP measurements of the uterus on the longitudinal and oblique transverse planes were significantly lower compared to the placebo group (p<0.05 and p<0.001, respectively).

conclusionDaily intake of Channa striatus extract results in marked differences compared to placebo in terms of uterine involution and recovery in women post LSCS.

trial registrationwww.isrctn.com 11960786.

Indexed as

Vascular ResistanceAdolescentAdultAnimalsDouble-Blind MethodFemaleFishesFollow-Up StudiesHumansSkin DiseasesTissue ExtractsTreatment OutcomeUterine ArteryUterusWound HealingWounds and InjuriesTissue Extracts

Identifiers

PMID26222158
PMCPMC4519193

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.