Evidence map›Paper›PMID 26222043›Full record

ArticleJAMA psychiatry2015

Association Between Social Integration and Suicide Among Women in the United States.

Alexander C Tsai, Michel Lucas, Ichiro Kawachi

Open access · bronzeAbstract read
In one paragraph

Article in JAMA psychiatry, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed
13.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 125 citations in OpenAlex.

  1. Trial
  2. A Pilot Randomized Trial of Engage Psychotherapy to Increase Social Connection and Reduce Suicide Risk in Later Life.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2021
    Trial
  3. Trial
  4. Trial
  5. Social cohesion, social capital and mental health: current evidence and future research directions.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2026
    Article
  6. Article
  7. The 5D indicators of suicide risk in older adults who are lonely.Annals of the New York Academy of Sciences · 2025
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Social Network Diversity and Mental Health Among Mothers of Individuals With Autism.American journal on intellectual and developmental disabilities · 2023
    Article
  13. Article
  14. Social isolation and suicide risk: Literature review and perspectives.European psychiatry : the journal of the Association of European Psychiatrists · 2022
    Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Social Disconnection in Late Life Suicide: An NIMH Workshop on State of the Research in Identifying Mechanisms, Treatment Targets, and Interventions.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2021
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 3 countries.

Alexander C Tsai *Center for Global Health, Massachusetts General Hospital, Boston, MA 02114, USA.
Michel Lucas *Department of Social and Preventive Medicine, Université Laval, Québec City, Québec G1V 2M2, Canada.
Ichiro KawachiDepartment of Social and Behavioral Sciences, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA.
Brigham and Women's Hospital · USHarvard University Press · USUniversité Laval · CA

Funding

Long Term Multidisciplinary Study of Cancer in Women: The Nurses Health StudyUM1CA186107 · NCI · BRIGHAM AND WOMEN'S HOSPITAL · PI ELIASSEN, A. HEATHER, STAMPFER, MEIR · 2014 to 2023
$22.3M
Microenterprise to empower and improve health of HIV+ women in UgandaK23MH096620 · NIMH · MASSACHUSETTS GENERAL HOSPITAL · PI TSAI, ALEXANDER C · 2012 to 2016
$922k
NCI NIH HHS UM1 CA186107NIMH NIH HHS K23 MH096620NIMH NIH HHS K23MH096620
6 · The paper itself

Abstract

importanceSuicide is one of the top 10 leading causes of mortality among middle-aged women. Most work in the field emphasizes the psychiatric, psychological, or biological determinants of suicide.

objectiveTo estimate the association between social integration and suicide. DESIGN, SETTING, AND

participantsWe used data from the Nurses' Health Study, an ongoing nationwide prospective cohort study of nurses in the United States. Beginning in 1992, a population-based sample of 72 607 nurses 46 to 71 years of age were surveyed about their social relationships. The vital status of study participants was ascertained through June 1, 2010. EXPOSURES: Social integration was measured with a 7-item index that included marital status, social network size, frequency of contact with social ties, and participation in religious or other social groups. MAIN OUTCOMES AND MEASURES: The primary outcome of interest was suicide, defined as deaths classified using the codes E950 to E959 from the International Classification of Diseases, Eighth Revision.

resultsDuring more than 1.2 million person-years of follow-up (1992-2010), there were 43 suicide events. The incidence of suicide decreased with increasing social integration. In a multivariable Cox proportional hazards regression model, the relative hazard of suicide was lowest among participants in the highest category of social integration (adjusted hazard ratio, 0.23 [95% CI, 0.09-0.58]) and second-highest category of social integration (adjusted hazard ratio, 0.26 [95% CI, 0.09-0.74]). Increasing or consistently high levels of social integration were associated with a lower risk of suicide. These findings were robust to sensitivity analyses that accounted for poor mental health and serious physical illness. CONCLUSIONS AND RELEVANCE: Women who were socially well integrated had a more than 3-fold lower risk for suicide over 18 years of follow-up.

Indexed as

Social SupportAgedCohort StudiesFemaleHumansIncidenceMarital StatusMiddle AgedMultivariate AnalysisProportional Hazards ModelsProspective StudiesSocial IsolationSocial ParticipationSuicideUnited StatesWomen

Identifiers

PMID26222043
PMCPMC4598291
OpenAlexW1925558682

What OpenQuestion holds

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LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.