Evidence map›Paper›PMID 26221952›Full record

ArticlePloS one2015

Prospectively ECG-Triggered Sequential Dual-Source Coronary CT Angiography in Patients with Atrial Fibrillation: Influence of Heart Rate on Image Quality and Evaluation of Diagnostic Accuracy.

Lin Yang, Lei Xu, U Joseph Schoepf, Julian L Wichmann, Mary A Fox, Jing Yan, Zhanming Fan, Zhaoqi Zhang

Abstract read
In one paragraph

Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. [The challenging patient-recommendations and solutions].Radiologie (Heidelberg, Germany) · 2024
    Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Functional Role and Mechanism of microRNA-28b in Atrial Myocyte in a Persistent Atrial Fibrillation Rat Model.Medical science monitor : international medical journal of experimental and clinical research · 2016
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Lin YangDepartment of Radiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.
Lei XuDepartment of Radiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.
U Joseph SchoepfDepartment of Radiology and Radiological Science, Medical University of South Carolina, Charleston, SC, United States of America.
Julian L WichmannDepartment of Radiology and Radiological Science, Medical University of South Carolina, Charleston, SC, United States of America.
Mary A FoxDepartment of Radiology and Radiological Science, Medical University of South Carolina, Charleston, SC, United States of America.
Jing YanSiemens Healthcare China, 278 Zhouzhu Road, Shanghai, China.
Zhanming FanDepartment of Radiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.
Zhaoqi ZhangDepartment of Radiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo evaluate the effects of mean heart rate (HR) and heart rate variation (HRV) on image quality and diagnostic accuracy of prospectively ECG-triggered sequential dual-source coronary CT angiography (CCTA) in patients with atrial fibrillation (AF).

methodsEighty-five patients (49 women, 36 men; mean age 62. 1 ± 9.5 years) with persistent AF underwent prospectively ECG-triggered sequential second-generation dual-source CCTA. Tube current and voltage were adjusted according to body mass index (BMI) and iterative reconstruction was used. Image quality of coronary segments (four-point scale) and presence of significant stenosis (>50%) were evaluated. Diagnostic accuracy was analyzed in 30 of the 85 patients who underwent additional invasive coronary angiography (ICA).

resultsOnly 8 of 1102 (0.7%) segments demonstrated poor image quality. No significant impact on image quality was found for mean HR (94.9 ± 21.8 bpm; r=0.034, p=0.758; F=0.413, p=0.663) or HRV (67.5 ± 22.8 bpm; r=0.097, p=0.377; F=0.111, p=0.895). On per-segment analysis, sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) were 89.7% (26/29), 99.4% (355/357), 92.9% (26/28), and 99.2% (355/358), respectively, with excellent correlation (kappa=0.91) with ICA. Mean effective dose was 3.3 ± 1.0 mSv.

conclusionsProspectively ECG-triggered sequential dual-source CCTA provides diagnostic image quality and good diagnostic accuracy for detection of coronary stenosis in AF patients without significant influence by HR or HRV.

Indexed as

AdultAgedAged, 80 and overAnalysis of VarianceAtrial FibrillationCardiac-Gated Imaging TechniquesCoronary AngiographyElectrocardiographyFemaleHeart RateHumansMaleMiddle AgedProspective StudiesRadiographic Image Interpretation, Computer-AssistedTomography, X-Ray Computed

Identifiers

PMID26221952
PMCPMC4519310

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.