ArticleJournal of applied oral science : revista FOB
Comparison of salivary levels of mucin and amylase and their relation with clinical parameters obtained from patients with aggressive and chronic periodontal disease.
Article in Journal of applied oral science : revista FOB. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05437874 (Effects of Carbonated Beverage Consumption on Oral pH and Bacterial Proliferation in Adolescents), which is not on this map. Cited by 15 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effects of Carbonated Beverage Consumption on Oral pH and Bacterial Proliferation in Adolescents: A Randomized Crossover Clinical Trial.
Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.
- Biomarkers for diagnosis of stage III, grade C with molar incisor pattern periodontitis in children and young adults: a systematic review and meta-analysis.Clinical oral investigations · 2023Pooled it
- An Overview of In Vitro Release Methods for Long-Acting Injectable Products Based on PLGA.Methods and protocols · 2026Review
- Association of salivary proteins with periodontal disease in children and adolescents- a scoping review.BMC oral health · 2026Article
- Salivary Markers as Potential Stress Descriptors for Pediatric Dental Patients: A Literature Review.Children (Basel, Switzerland) · 2025Review
- Exploring Salivary Alpha-Amylase as a Biomarker in Periodontitis: A Comparative Analysis of Disease Stages and Clinical Correlations.Current issues in molecular biology · 2024Article
- Filtered Saliva for Rapid and Accurate Analyte Detection for POC Diagnostics.Diagnostics (Basel, Switzerland) · 2024Article
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- Effects of Carbonated Beverage Consumption on Oral pH and Bacterial Proliferation in Adolescents: A Randomized Crossover Clinical Trial.Life (Basel, Switzerland) · 2022Article
- Assessing suspension and infectivity times of virus-loaded aerosols involved in airborne transmission.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Assessment of salivary alpha amylase and mucin-4 before and after non-surgical treatment of peri-implant mucositis.International journal of implant dentistry · 2022Article
- Mucins Inhibit Coronavirus Infection in a Glycan-Dependent Manner.ACS central science · 2022Article
- An enhanced isothermal amplification assay for viral detection.Nature communications · 2020Article
- Mucin 4 and matrix metalloproteinase 7 as novel salivary biomarkers for periodontitis.Journal of clinical periodontology · 2017Article
- Comparative evaluation of mucin and total protein in periodontal disease before and after nonsurgical periodontal therapy.Journal of Indian Society of PeriodontologyArticle
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveSalivary mucin and amylase levels are increased in patients with chronic periodontitis (CP). Due to the fact that aggressive periodontitis (AgP) not only differs from chronic periodontitis in terms of its clinical manifestation, the aim of this study was to compare salivary mucin and amylase levels and their relation to the clinical parameters of patients with aggressive periodontitis with that of patients with chronic periodontitis. MATERIAL AND
methodsEighty subjects were divided into two groups: 20 patients with AgP and their 20 matched controls and 20 patients with CP and their 20 matched controls, based on clinical attachment loss (CAL), probing pocket depth (PPD) and bleeding on probing (BOP). Whole unstimulated saliva was obtained and mucin, amylase and protein were determined by colorimetric methods. Pearson's correlation analysis was used to determine the relationship between salivary mucin, amylase and protein levels and the clinical parameters.
resultsSalivary mucin, amylase and protein levels were increased in patients with AgP and CP but there were no differences between them or between control groups. Pearson's correlation analysis, determined in the entire subjects studied, showed a positive and significant correlation of mucin, amylase and proteins with CAL and PPD and a negative correlation with the flow rate. When Pearson's correlation analysis was carried out in each group separately, Fisher's z transformation showed no significant difference between both groups.
conclusionComparison of the salivary levels of mucin, amylase and protein and their relationship with clinical parameters of AgP patients with that of CP patients revealed no differences between both groups.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.