ArticleCaspian journal of internal medicine2015
Relationship between Helicobacter pylori infection (HP) and bone mineral density (BMD) in elderly people.
Article in Caspian journal of internal medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.
- Relationship betweenBMJ open · 2019Pooled it
- Clinical features and shared mechanisms of chronic gastritis and osteoporosis.Scientific reports · 2023Article
- Bone Fragility in Gastrointestinal Disorders.International journal of molecular sciences · 2022Review
- The Association betweenMediators of inflammation · 2022Article
- Effect of sequential eradication therapy on serum osteoprotegerin levels in patients withThe Journal of international medical research · 2021Observational
- Effect of Naringin Treatment on Postmenopausal Osteoporosis in Ovariectomized Rats: A Meta-Analysis and Systematic Review.Evidence-based complementary and alternative medicine : eCAM · 2021Article
- Helicobacter pylori Related Diseases and Osteoporotic Fractures (Narrative Review).Journal of clinical medicine · 2020Review
- Role of Helicobacter pylori infection in the manifestation of old age-related diseases.Molecular genetics & genomic medicine · 2020Review
- Bone of Contention: Helicobacter pylori and Osteoporosis-Is There an Association?Digestive diseases and sciences · 2019Review
- Relationship between Helicobacter pylori infection and bone mineral density: a retrospective cross-sectional study.BMC gastroenterology · 2018Article
- Correlation betweenGastroenterology research and practice · 2018Article
- Cohort Profile Update: The Amirkola Health and Ageing Project (AHAP).Caspian journal of internal medicine · 2017Article
- Article
- Helicobacter pylori infection and osteoporosis in elderly patients.Caspian journal of internal medicine · 2015Article
Corrections and comments
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundLow bone mass is a frequent complication of chronic inflammatory disease. The pathogenesis of osteoporosis in chronic inflammatory disease may be secondary to releases of cytokines such as TNF- and IL6. Chronic gastritis due to helicobacter pylori (HP) infection may lead to decreased bone mineral density (BMD) and predispose patients to osteoporosis. The objective of this study was to determine the BMD status in HP positive patients with gastritis versus HP negative cases.
methodsIn this cross-sectional study, we enrolled 967 participants aged 60 years old and more from Amirkola Health Study Ageing Project. Seven-hundred and fifty eight HP positive and 209 HP negative patients were analyzed. BMD was measured by dual-energy x-ray absorptiometry (DXA) method in the spine and femoral neck in all participants.
resultsThe mean age in HP+ and HP- negative patients was 68.3±6.8 and 69.3±7.4 years, respectively. BMD g/cm2 in the spine and femoral neck did not differ between the two groups (P=0.19 and 0.22 respectively). The prevalence of osteoporosis did not also differ across the two groups as well. There was no relationship between the level of antibodies against HP and BMD.
conclusionAccording to the findings of this study, H. pylori infection is not associated with BMD changes in the elderly population.
Indexed as
Identifiers
26221501PMC4478452W2281712942What OpenQuestion holds
Registered trials
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