ArticleInternational journal of clinical and experimental medicine2015
Association of CYP2J2 gene polymorphisms with ischemic stroke.
Article in International journal of clinical and experimental medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
What it found
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The trial behind it
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.
- Association of CYP2J2 gene polymorphisms with ischemic stroke and stroke subtypes in Chinese population.Medicine · 2017Pooled it
- Characterization of 15 CYP2J2 variants identified in the Chinese Han population on the metabolism of ebastine and terfenadineFrontiers in pharmacology · 2023Article
- Analysis ofAmerican journal of translational research · 2021Article
- CYP2J2 Molecular Recognition: A New Axis for Therapeutic Design.Pharmacology & therapeutics · 2020Review
- A comprehensive study revealed SNP-SNP interactions and a sex-dependent relationship between polymorphisms of the CYP2J2 gene and hypertension risk.Hypertension research : official journal of the Japanese Society of Hypertension · 2019Article
- Genetic polymorphisms of the drug-metabolizing enzyme CYP2J2 in a Tibetan population.Medicine · 2018Observational
- Regulation of CYP2J2 and EET Levels in Cardiac Disease and Diabetes.International journal of molecular sciences · 2018Review
- The impact of the AHSG genetic polymorphism on the risk of ischemic stroke: a case-control study.International journal of clinical and experimental pathology · 2018Article
- CYP2J2 participates in atherogenesis by mediating cell proliferation, migration and foam cell formation.Molecular medicine reports · 2017Article
- Association of CYP2J2 polymorphism with susceptibility to psoriasis in Turkish population: a case-control study.Anais brasileiros de dermatologiaArticle
- Role of cytochrome epoxygenase (CYP2J2) in the pathophysiology of coronary artery disease in South Indian population.Indian heart journalArticle
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe present study aims to investigate the relationship between CYP2J2 gene polymorphisms and ischemic stroke (IS) in a Chinese Han population.
methodsWe performed a case-control study including 300 stroke patients and 300 healthy control subjects to compare the distribution of genetic polymorphism G-50T in CYP2J2 gene.
resultsWe found GT genotype of G-50T in CYP2J2 gene was associated with the risk for IS (13.7% vs. 7.7%, P = 0.037). After adjustment of confounders, the difference remains significant (OR = 1.890, 95% CI: 1.042-3.011).
conclusionCYP2J2 gene polymorphism might increase the risk of stroke in Chinese population.
Indexed as
Identifiers
26221386PMC4509331W2224907889What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.