ArticleInternational journal of clinical and experimental medicine2015
The therapeutic effect of Xueshuan Xinmai tablets on memory injury and brain activity in post-stroke patients: a pilot placebo controlled fMRI study.
Article in International journal of clinical and experimental medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The trial behind it
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Who cites it
2 citing papers in PubMed.
- A Two-Year Treatment of Amnestic Mild Cognitive Impairment using a Compound Chinese Medicine: A Placebo Controlled Randomized Trial.Scientific reports · 2016Trial
- Pilot and feasibility trials in traditional Chinese medicine: a literature review of current practice.Pilot and feasibility studies · 2020Article
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Authors and funding
7 authors.
Funding
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Abstract
objectiveThe purpose of this study was to explore the effects of Xueshuan Xinmai tablets (XXMT) for the treatment of cognition, brain activation in the rehabilitation period of ischemic stroke patients.
methods28 adults patients, aged 50-80 years, in the rehabilitation period of ischemic stroke were divided into XXMT treatment group and placebo control group. Patients received 3 months treatment (oral 0.8 g, 3 times per day). Before and after treatment, all patients were evaluated by a series of neuropsychological tests followed by resting-state functional magnetic resonance imaging (fMRI).
resultsIn the XXMT treatment group, the patients' episodic memory showed significant improvement. The resting-state fMRI analysis indicated that a significant decline in the fractional amplitude of low-frequency fluctuation value was observed in the bilateral middle cingulate gyrus.
conclusionsYiqi Huoxue effect under XXMT administration has a favorable mediation on episodic memory, consequently suppresses the activation of the cingulate gyrus in the rehabilitation period of ischemic stroke patients.
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26221294PMC4509239What OpenQuestion holds
Registered trials
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