Evidence map›Paper›PMID 26221192›Full record

ArticleThe EPMA journal2015

Probiotics and immunity: provisional role for personalized diets and disease prevention.

Rostyslav V Bubnov, Mykola Ya Spivak, Liudmyla M Lazarenko, Alojz Bomba, Nadiya V Boyko

Abstract read
In one paragraph

Article in The EPMA journal, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed.

  1. Effects of pentasa-combined probiotics on the microflora structure and prognosis of patients with inflammatory bowel disease.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2019
    Trial
  2. Review
  3. Review
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  7. Review
  8. Article
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  10. Article
  11. Article
  12. Article
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  14. TheRSC advances · 2022
    Article
  15. Article
  16. Frontiers in microbiology · 2022
    Article
  17. Article
  18. Review
  19. Review
  20. Journal of inflammation research · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Rostyslav V BubnovZabolotny Institute of Microbiology and Virology, National Academy of Sciences of Ukraine, 154, Zabolotny St., Kyiv, 03680 Ukraine ; Clinical Hospital "Pheophania" of State Affairs Department, Zabolotny Str., 21, Kyiv, 03680 Ukraine.
Mykola Ya SpivakZabolotny Institute of Microbiology and Virology, National Academy of Sciences of Ukraine, 154, Zabolotny St., Kyiv, 03680 Ukraine ; LCL "Diaprof", Svitlycky Str., 35, Kyiv, 04123 Ukraine.
Liudmyla M LazarenkoZabolotny Institute of Microbiology and Virology, National Academy of Sciences of Ukraine, 154, Zabolotny St., Kyiv, 03680 Ukraine.
Alojz BombaCassovia Life Sciences, Palárikova 4, 04011 Košice, Slovak Republiс ; Institute of Experimental Medicine, Faculty of Medicine, Pavol Jozef Šafárik University in Košice, Trieda SNP 1, 04011 Košice, Slovak Republiс
Nadiya V BoykoZabolotny Institute of Microbiology and Virology, National Academy of Sciences of Ukraine, 154, Zabolotny St., Kyiv, 03680 Ukraine ; Cassovia Life Sciences, Palárikova 4, 04011 Košice, Slovak Republiс

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There is great interest in the interaction between diet and immune system and concomitantly in the potential of probiotic bacteria, especially given recent advances in understanding of gut microbiota effects on health in the context of microbiome research. Following our recent study on bacterial wall elasticity as a predictive measure of phagocytic cellular reactions and related outcomes, a question was raised regarding the scope of the application of these findings in various medical conditions in the context of predictive, preventive, and personalized medicine (PPPM). This summarizing review of the data describes the contributions, both observed and potential, of probiotics to the gut-brain axis and various medical conditions, including immune and atopic states, metabolic and inflammatory diseases-including liver disease and diabetes mellitus-cancer, and more. It also suggests novel insights for a number of beneficial applications of probiotics and advances in development of novel probiotic-based treatments and personalized diets, as well as application of sophisticated imaging techniques and nanobiotechnologies that can be adopted in the near future by innovative medical experts, warranting further research and practical translation.

Indexed as

and personalized medicineBifidobacteriumCancerDietary biomarkersFecal microbiota transplantationGut-brain axisGut microbiotaHealthy dietImmune disordersLactobacillusMicrobiomeNutritionPattern recognition receptorsPredictivePreventive

Identifiers

PMID26221192
PMCPMC4517425

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.