Evidence map›Paper›PMID 26221098›Full record

ArticleBrazilian journal of microbiology : [publication of the Brazilian Society for Microbiology]2015

Adherence and virulence genes of Escherichia coli from children diarrhoea in the Brazilian Amazon.

Najla Benevides-Matos, Fabio A Pieri, Marilene Penatti, Patrícia P Orlandi

Open access · hybridAbstract read
In one paragraph

Article in Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology], 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Beneficial role of skim milk against drug-resistantNew microbes and new infections · 2022
    Article
  3. Article
  4. Prevalence of diarrheagenicIranian journal of veterinary research · 2019
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Najla Benevides-MatosInstituto de Pesquisas em Patologias Tropicais, Fundação Oswaldo Cruz, Porto Velho, RO, Brazil.
Fabio A PieriInstituto Leônidas e Maria Deane, Fundação Oswaldo Cruz, Manaus, AM, Brazil.
Marilene PenattiHospital Infantil Cosme e Damião, Secretaria de Estado da Saúde, Porto Velho, RO, Brazil.
Patrícia P OrlandiInstituto Leônidas e Maria Deane, Fundação Oswaldo Cruz, Manaus, AM, Brazil.
Fundação Oswaldo Cruz · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The bacterial pathogen most commonly associated with endemic forms of childhood diarrhoea is Escherichia coli . Studies of epidemiological characteristics of HEp-2 cell-adherent E. coli in diarrhoeal disease are required, particularly in developing countries. The aim of this study was evaluate the presence and significance of adherent Escherichia coli from diarrhoeal disease in children. The prevalence of LA, AA, and DA adherence patterns were determined in HEp-2 cells, the presence of virulence genes and the presence of the O serogroups in samples obtained from 470 children with acute diarrhoea and 407 controls in Porto Velho, Rondônia, Brazil. E. coli isolates were identified by PCR specific for groups of adherent E. coli . Out of 1,156 isolates obtained, 128 (11.0%) were positive for eae genes corresponding to EPEC, however only 38 (29.6%) of these amplified bfpA gene . EAEC were isolated from 164 (14.1%) samples; of those 41(25%), 32 (19%) and 16 (9.7%) amplified eagg , aggA or aafA genes, respectively and aggA was significantly associated with diarrhoea ( P = 0.00006). DAEC identified by their adhesion pattern and there were few isolates. In conclusion, EAEC was the main cause of diarrhoea in children, especially when the aggA gene was present, followed by EPEC and with a negligible presence of DAEC.

Indexed as

Bacterial AdhesionBrazilChildChild, PreschoolDiarrheaEnteropathogenic Escherichia coliEpithelial CellsEscherichia coliEscherichia coli InfectionsHumansInfantInfant, NewbornO AntigensSerogroupVirulence FactorsO AntigensVirulence FactorschildrendiarrhoeaEnteroadherent Escherichia coli

Identifiers

PMID26221098
PMCPMC4512055
OpenAlexW2260937340

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.