ArticleBrazilian journal of microbiology : [publication of the Brazilian Society for Microbiology]2015
Clinical significance of the isolation of Candida species from hospitalized patients.
Article in Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology], 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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14 citing papers in PubMed.
- Fluconazole-resistant vulvovaginal candidiasis in reproductive-age women: a study from Himalayan country.BMC microbiology · 2025Article
- Clinical Isolate ofOpen journal of medical microbiology · 2025Article
- Trichosporon Urinary Tract Infections: A Hidden Menace Revealed.Iranian journal of pathology · 2025Review
- Exploring the Biology, Virulence, and General Aspects ofInfection and drug resistance · 2024Review
- Rare Yeasts in Latin America: Uncommon Yet Meaningful.Journal of fungi (Basel, Switzerland) · 2023Review
- Article
- Medically important Candida spp. identification: an era beyond traditional methods.Turkish journal of medical sciences · 2022Article
- Rationales Design von Phe-BODIPY-Aminosäuren als fluorogene Bausteine für den peptidbasierten Nachweis vonAngewandte Chemie (Weinheim an der Bergstrasse, Germany) · 2022Article
- Rational Design of Phe-BODIPY Amino Acids as Fluorogenic Building Blocks for Peptide-Based Detection of Urinary Tract Candida Infections.Angewandte Chemie (International ed. in English) · 2022Article
- Article
- Molecular identification and antifungal susceptibility pattern ofCurrent medical mycology · 2019Article
- An Invertebrate Host to Study Fungal Infections, Mycotoxins and Antifungal Drugs:Journal of fungi (Basel, Switzerland) · 2018Review
- The epidemiology of cryptococcosis and the characterization of Cryptococcus neoformans isolated in a Brazilian University Hospital.Revista do Instituto de Medicina Tropical de Sao Paulo · 2017Article
- Spectrum of Opportunistic Fungal Infections in HIV/AIDS Patients in Tertiary Care Hospital in India.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2016Article
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7 authors.
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Abstract
In this study, we isolated and phenotypically identified 108 yeast strains from various clinical specimens collected from 100 hospitalized patients at three tertiary hospitals in São Luís-Maranhão, Brazil, from July to December 2010. The isolates were analyzed for their susceptibility to four of the most widely used antifungal agents in the surveyed hospitals, amphotericin B, fluconazole, 5-flucytosine and voriconazole. The species identified were Candida albicans (41.4%), Candida tropicalis (30.1%), C. glabrata (7.4%), Candida parapsilosis (5.5%), Candida krusei (4.6%), Cryptococcus neoformans (4.6%), Trichosporon spp . (3.7%), Candida norvegensis (0.9%), Rhodotorula glutinis (0.9%) and Pichia farinosa (0.9%). A higher isolation rate was observed in the following clinical specimens: urine (54 isolates; 50%), respiratory tract samples (21 isolates; 19.4%) and blood (20 isolates; 18.6%). Candida albicans isolates were 100% sensitive to all antifungal agents tested, whereas Candida krusei and Crytococcus neoformans displayed intermediate resistance to 5-flucytosine, with Minimal Inhibitory Concentration (MIC) values of 8 mg/mL and 16 mg/mL, respectively. Both strains were also S-DD to fluconazole with an MIC of 16 mg/mL. C. tropicalis was resistant to 5-flucytosine with an MIC of 32 μg/mL. This study demonstrates the importance of identifying the yeast species involved in community and nosocomial infections.
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