ArticleScientific reports2015
Timing of diffusion tensor imaging in the acute spinal cord injury of rats.
Article in Scientific reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
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Who cites it
28 citing papers in PubMed.
- Progressive Remote Axonal Degeneration Following Spinal Cord Injury: A Histological and MRI Study.Neurotrauma reports · 2025Article
- Diffusion Weighted Magnetic Resonance Imaging of Spinal Cord Injuries After Instrumented Fusion Stabilization.Journal of neurotrauma · 2024Article
- Porcine Model of the Growing Spinal Cord-Changes in Diffusion Tensor Imaging Parameters.Animals : an open access journal from MDPI · 2023Article
- Quantitative Analysis in Cervical Spinal Cord Injury Patients Using Diffusion Tensor Imaging and Tractography.Annals of rehabilitation medicine · 2022Article
- Assessment of acute traumatic cervical spinal cord injury using conventional magnetic resonance imaging in combination with diffusion tensor imaging-tractography: a retrospective comparative study.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2022Article
- Article
- Trihydroxyethyl Rutin Provides Neuroprotection in Rats With Cervical Spinal Cord Hemi-Contusion.Frontiers in neuroscience · 2021Article
- Article
- Correlation of blunt cervical spinal cord injury magnetic resonance imaging tractography with the American Spinal Injury Association impairment scale motor scores.SA journal of radiology · 2021Article
- Longitudinal assessment of recovery after spinal cord injury with behavioral measures and diffusion, quantitative magnetization transfer and functional magnetic resonance imaging.NMR in biomedicine · 2020Article
- Correlation of Clinical Findings in Acute Spinal Injury Patients with Magnetic Resonance Including Diffusion Tensor Imaging and Fiber Tractography.Spine surgery and related research · 2020Article
- Traumatic and nontraumatic spinal cord injury: pathological insights from neuroimaging.Nature reviews. Neurology · 2019Review
- Diffusion tensor imaging predicting neurological repair of spinal cord injury with transplanting collagen/chitosan scaffold binding bFGF.Journal of materials science. Materials in medicine · 2019Article
- Cellular Inflammatory Response of the Spleen After Acute Spinal Cord Injury in Rat.Inflammation · 2019Article
- Evaluation of hyperbaric oxygen therapy for spinal cord injury in rats with different treatment course using diffusion tensor imaging.Spinal cord · 2019Article
- Imaging findings of penetrating spinal cord injuries secondary to stab wounds on magnetic resonance imaging in a tertiary trauma unit, South Africa.SA journal of radiology · 2019Article
- Lithium promotes recovery of neurological function after spinal cord injury by inducing autophagy.Neural regeneration research · 2018Article
- Evaluation of Hyperbaric Oxygen Treatment in Acute Traumatic Spinal Cord Injury in Rats Using Diffusion Tensor Imaging.Aging and disease · 2018Article
- Spontaneous acute and chronic spinal cord injuries in paraplegic dogs: a comparative study of in vivo diffusion tensor imaging.Spinal cord · 2017Observational
- Feasibility of Diffusion Tensor Imaging for Assessing Functional Recovery in Rats with Olfactory Ensheathing Cell Transplantation After Contusive Spinal Cord Injury (SCI).Medical science monitor : international medical journal of experimental and clinical research · 2017Article
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aim of this study was to evaluate the characteristics of magnetic resonance diffusion tensor imaging (DTI) in acute spinal cord following a thoracic spinal cord injury (SCI), and to determine the optimal time of examination. Sprague-Dawley rats were used as experimental animals and contusion injuries were made at the T10 vertebral level. The rats were divided into control, mild injury, moderate injury, and severe injury groups. Spinal magnetic resonance DTI was scheduled at 6, 24 and 72 hours (h) post-SCI, and the DTI parameters such as fractional anisotropy (FA) and apparent diffusion coefficient (ADC) were calculated, and the diffusion tensor tractography (DTT) of the spinal cord was also generated. We observed a significant decrease of FA in all the three injured groups, and the FA at 24 h post-SCI exhibited the greatest decrease among different set times. For ADC, only the group of severely injured rats saw a significant decrease at 24 and 72 h compared with the control group. DTT showed interruption of nerve fiber tracking in the injured groups. This study demonstrates that FA can differentiate various grades of SCI in the early stage, and 24 h after injury might be the optimal time for identifying injury severity.
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