Evidence map›Paper›PMID 26220592›Full record

ArticleTwin research and human genetics : the official journal of the International Society for Twin Studies2015

Missouri Mothers and Their Children: A Family Study of the Effects of Genetics and the Prenatal Environment.

Valerie S Knopik, Andrew C Heath, Kristine Marceau, Rohan H C Palmer, John E McGeary, Alexandre Todorov, Allison Schettini Evans

Open access · bronzeAbstract readTwin Study
In one paragraph

Article in Twin research and human genetics : the official journal of the International Society for Twin Studies, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
13.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Disruptive Behavior in Siblings Discordant for Exposure to Maternal Smoking During Pregnancy: A Multi-rater Approach.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2020
    Article
  5. Article
  6. Article
  7. Article
  8. Smoking during pregnancy and ADHD risk: A genetically informed, multiple-rater approach.American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics · 2016
    Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Valerie S KnopikDivision of Behavioral Genetics,Rhode Island Hospital;Department of Psychiatry and Human Behavior,Brown University,Providence,Rhode Island,USA.
Andrew C HeathMidwest Alcoholism Research Center,Department of Psychiatry,Washington University School of Medicine,St Louis,Missouri,USA.
Kristine MarceauCenter for Alcohol and Addiction Studies,Brown University,Providence,Rhode Island,USA.
Rohan H C PalmerDivision of Behavioral Genetics,Rhode Island Hospital;Department of Psychiatry and Human Behavior,Brown University,Providence,Rhode Island,USA.
John E McGearyProvidence Veterans Affairs Medical Center,Providence,Rhode Island,USA.
Alexandre TodorovDepartment of Psychiatry,Washington University School of Medicine,St Louis,Missouri,USA.
Allison Schettini EvansMemorial Hospital,Pawtucket,Rhode Island,USA.
Rhode Island Hospital · USWashington University in St. Louis · USBrown University · USMemorial Hospital of Rhode Island · US

Funding

PILOT--GENETIC EPIDEMIOLOGY OF ALCOHOL AND TOBACCO CONSUMPTION IN CHINESE SAMPLEP50AA011998 · NIAAA · WASHINGTON UNIVERSITY · PI SHER, KENNETH JAMES · 1999 to 2008
$12.6M
Resource CoreP60AA011998 · NIAAA · WASHINGTON UNIVERSITY · PI MADDEN, PAMELA ANN · 2009 to 2013
$8.8M
Substance Abuse Intervention/Outcome Research TrainingT32DA016184 · NIDA · BROWN UNIVERSITY · PI Damaris J. Rohsenow, JENNIFER W. TIDEY · 2003 to 2026
$6.1M
ALCOHOLISM: GENETIC EPIDEMIOLOGIC TWIN STUDYR01AA009022 · NIAAA · WASHINGTON UNIVERSITY · PI HEATH, ANDREW C. · 1994 to 2004
$3.3M
GxE in Early Childhood: Twin MothersR01HD049024 · NICHD · WASHINGTON UNIVERSITY · PI HEATH, ANDREW C. · 2005 to 2009
$2.9M
Prenatal tobacco exposure: effects on neuropsychological outcomes and ADHDR01DA023134 · NIDA · RHODE ISLAND HOSPITAL · PI KNOPIK, VALERIE S · 2008 to 2013
$2.7M
Genetic Epideniologic Models of Alcohol AbuseR37AA007728 · NIAAA · WASHINGTON UNIVERSITY · PI HEATH, ANDREW C. · 1998 to 2007
$2.2M
GENE-ENVIRONMENT INTERPLAY IN ALCOHOLISMK05AA017688 · NIAAA · WASHINGTON UNIVERSITY · PI HEATH, ANDREW C. · 2008 to 2017
$1.9M
NEIGHBORHOOD, FAMILY AND INDIVIDUAL FACTORS IN ADOLESCENT DRINKINGR01AA021492 · NIAAA · WASHINGTON UNIVERSITY · PI HEATH, ANDREW C., SCHOOTMAN, MARIO · 2013 to 2016
$1.2M
Systems Genetics of Alcoholism: Network-based Approaches for Genetics AssociationK01AA021113 · NIAAA · RHODE ISLAND HOSPITAL · PI PALMER, ROHAN HUGH CRAIG · 2012 to 2016
$838k
Externalizing Behavior: Genetics x Prenatal NicotineK01DA017671 · NIDA · WASHINGTON UNIVERSITY · PI KNOPIK, VALERIE S · 2004 to 2008
$813k
NATURAL HISTORY OF ALCOHOL USE &ABUSE--GENETIC MODELSR01AA007728 · NIAAA · WASHINGTON UNIVERSITY · PI HEATH, ANDREW C. · 1988 to 1998
–
NCATS NIH HHS L30 TR001045NIAAA NIH HHS AA017688NIAAA NIH HHS AA021492NIAAA NIH HHS AA07728NIAAA NIH HHS AA09022NIAAA NIH HHS AA11998NIAAA NIH HHS K01 AA021113NIAAA NIH HHS K01AA021113NIAAA NIH HHS K05 AA017688NIAAA NIH HHS P50 AA011998NIAAA NIH HHS R01 AA007728NIAAA NIH HHS R01 AA009022NIAAA NIH HHS R01 AA021492NIAAA NIH HHS R37 AA007728NICHD NIH HHS HD049024NICHD NIH HHS R01 HD049024NIDA NIH HHS DA023134NIDA NIH HHS DA17671NIDA NIH HHS K01 DA017671NIDA NIH HHS R01 DA023134NIDA NIH HHS T32 DA016184
6 · The paper itself

Abstract

The Missouri Mothers and Their Children Study (MO-MATCH) was specifically designed to critically investigate prenatal environmental influences on child attention problems and associated learning and cognitive deficits. The project began as a pilot study in 2004 and was formally launched in 2008. Participants in the study were initially identified via the Department of Vital Statistics birth record (BR) database. Interview and lab-based data were obtained from: (1) mothers of Missouri-born children (born 1998-2005), who smoked during one pregnancy but not during another pregnancy; (2) biological fathers when available; and (3) the children (i.e., full sibling pairs discordant for exposure to maternal smoking during pregnancy (SDP). This within-mother, between-pregnancy contrast provides the best possible methodological control for many stable maternal and familial confounding factors (e.g., heritable and socio-demographic characteristics of the mother that predict increased probability of SDP). It also controls for differences between mothers who do and do not smoke during pregnancy, and their partners, that might otherwise artifactually create, or alternatively mask, associations between SDP and child outcomes. Such a design will therefore provide opportunities to determine less biased effect sizes while also allowing us to investigate (on a preliminary basis) the possible contribution of paternal or other second-hand smoke exposure during the pre, peri, and postnatal periods to offspring outcome. This protocol has developed a cohort that can be followed longitudinally through periods typically associated with increased externalizing symptoms and substance used initiation.

Indexed as

Child DevelopmentCognitionGene-Environment InteractionAdolescentAdultChildEnvironmentFemaleHumansMaleMiddle AgedMissouriMothersPilot ProjectsPregnancyPrenatal Exposure Delayed Effectsfamily studygeneticsquasi-experimental designsibling comparisonsmoking during pregnancy

Identifiers

PMID26220592
PMCPMC4631647
OpenAlexW1873416920

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.