Evidence map›Paper›PMID 26220521›Full record

ArticleEuropean journal of epidemiology2016

Physical activity is associated with lower arterial stiffness in older adults: results of the SAPALDIA 3 Cohort Study.

Simon Endes, Emmanuel Schaffner, Seraina Caviezel, Julia Dratva, Christine Sonja Autenrieth, Miriam Wanner, Brian Martin, Daiana Stolz, Marco Pons, Alexander Turk and 5 more

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In one paragraph

Article in European journal of epidemiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
5.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it, 61 citations in OpenAlex.

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  4. Hypertensive women with dyspnea exhibit an unfavorable central blood pressure response to exercise.Hypertension research : official journal of the Japanese Society of Hypertension · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 7 institutions in 2 countries.

Simon EndesDivision of Sports and Exercise Medicine, Department of Sport, Exercise and Health, University of Basel, Birsstrasse 320B, 4052, Basel, Switzerland. simon.endes@unibas.ch.ORCID http://orcid.org/0000-0002-2193-0114
Emmanuel SchaffnerSwiss Tropical and Public Health Institute, Basel, Switzerland.
Seraina CaviezelSwiss Tropical and Public Health Institute, Basel, Switzerland.
Julia DratvaSwiss Tropical and Public Health Institute, Basel, Switzerland.
Christine Sonja AutenriethSwiss Tropical and Public Health Institute, Basel, Switzerland.
Miriam WannerPhysical Activity and Health Working Unit, Institute of Social and Preventive Medicine, University of Zurich, Zurich, Switzerland.
Brian MartinPhysical Activity and Health Working Unit, Institute of Social and Preventive Medicine, University of Zurich, Zurich, Switzerland.
Daiana StolzClinic of Pneumology and Respiratory Cell Research, University Hospital, Basel, Switzerland.
Marco PonsDivision of Pulmonary Medicine, Regional Hospital Lugano, Lugano, Switzerland.
Alexander TurkZürcher Höhenklinik, Wald-Faltigberg, Faltigberg-Wald, Switzerland.
Robert BettschartLungenpraxis Hirslanden Klinik Aarau, Aarau, Switzerland.
Christian SchindlerSwiss Tropical and Public Health Institute, Basel, Switzerland.
Nino KünzliSwiss Tropical and Public Health Institute, Basel, Switzerland.
Nicole Probst-HenschSwiss Tropical and Public Health Institute, Basel, Switzerland.
Arno Schmidt-TrucksässDivision of Sports and Exercise Medicine, Department of Sport, Exercise and Health, University of Basel, Birsstrasse 320B, 4052, Basel, Switzerland.
Swiss Tropical and Public Health Institute · CHUniversity of Basel · CHUniversity of Zurich · CHHirslanden Klinik Aarau · CHOspedale regionale di Lugano · CHUniversity Hospital of Basel · CHZürcher RehaZentrum Davos · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Associations of physical activity (PA) intensity with arterial stiffness in older adults at the population level are insufficiently studied. We examined cross-sectional associations of self-reported PA intensities with arterial stiffness in elderly Caucasians of the Swiss Cohort Study on Air Pollution and Lung and Heart Diseases in Adults. Mixed central and peripheral arterial stiffness was measured oscillometrically by the cardio-ankle vascular index (CAVI) and brachial-ankle pulse wave velocity (baPWV). The self-reported International Physical Activity Questionnaire long version was administered to classify each subject's PA level. We used univariable and multivariable mixed linear and logistic regression models for analyses in 1908 persons aged 50 years and older. After adjustment for several confounders moderate, vigorous and total PA were inversely associated with CAVI (p = 0.02-0.03). BaPWV showed negative and marginally significant associations with vigorous and moderate PA (each p = 0.06), but not with total PA (p = 0.28). Increased arterial stiffness (CAVI ≥ 9, upper tertile) was inversely and significantly associated with vigorous PA [odds ratio (OR) 0.65, 95% confidence interval (CI) 0.48-0.88], and marginally significantly with total PA (OR 0.76, 95% CI 0.57-1.02) and moderate PA (OR 0.75, 95% CI 0.56-1.01). The odds ratio for baPWV ≥ 14.4 was 0.67 (95% CI 0.48-0.93) across the vigorous PA levels, and was non-significant across the total (OR 0.91, 95% CI 0.66-1.23) and moderate PA levels (OR 0.94, 95% CI 0.69-1.28). In this general Caucasian population of older adults higher levels especially of vigorous PA were associated with lower arterial stiffness. These data support the importance of PA for improving cardiovascular health in elderly people.

Indexed as

AgingMotor ActivityAdultAgedAged, 80 and overAnkle Brachial IndexCross-Sectional StudiesFemaleGeriatric AssessmentHumansLife StyleLongitudinal StudiesMaleMiddle AgedOdds RatioPulse Wave AnalysisArterial stiffnessCardiovascular disease preventionEpidemiologyPhysical exercisePrevention

Identifiers

PMID26220521
OpenAlexW1845950631

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.