ArticleThe Science of the total environment2015
Autism spectrum disorder prevalence and proximity to industrial facilities releasing arsenic, lead or mercury.
Article in The Science of the total environment, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
35 citing papers in PubMed, 89 citations in OpenAlex.
- Prenatal ozone exposure and risk of intellectual disability.Journal of exposure science & environmental epidemiology · 2026Article
- Observational methods for human studies of transgenerational effects.Epigenetics · 2024Article
- An ecological study shows increased prevalence of autism spectrum disorder in children living in a heavily polluted area.Scientific reports · 2024Article
- Neurogenic Effects of Inorganic Arsenic and Cdk5 Knockdown in Zebrafish Embryos: A Perspective on Modeling Autism.International journal of molecular sciences · 2024Review
- Identification of novel NRF2-dependent genes as regulators of lead and arsenic toxicity in neural progenitor cells.Journal of hazardous materials · 2024Article
- Environmental Influences on Individuals with Autistic Spectrum Disorders with Special Emphasis on Seasonality: An Overview.Children (Basel, Switzerland) · 2023Review
- Examining the effects of cumulative environmental stressors on Gulf Coast child and adolescent health.Population and environment · 2023Article
- Disparities in Toxic Chemical Exposures and Associated Neurodevelopmental Outcomes: A Scoping Review and Systematic Evidence Map of the Epidemiological Literature.Environmental health perspectives · 2023Article
- Selection of Young Animal Models of Autism over Adult: Benefits and Limitations.Integrative psychological & behavioral science · 2023Article
- Prenatal socioenvironmental exposures and autism spectrum disorder: A web of confusion.Child development perspectives · 2023Article
- Association between heavy metals exposure (cadmium, lead, arsenic, mercury) and child autistic disorder: a systematic review and meta-analysis.Frontiers in pediatrics · 2023Article
- Metal Profiles in Autism Spectrum Disorders: A Crosstalk between Toxic and Essential Metals.International journal of molecular sciences · 2022Review
- Evidence of transgenerational effects on autism spectrum disorder using multigenerational space-time cluster detection.International journal of health geographics · 2022Article
- Associations between estimates of perinatal industrial pollution exposures and intellectual disability in Utah children.The Science of the total environment · 2022Article
- Environmental exposures associated with elevated risk for autism spectrum disorder may augment the burden of deleterious de novo mutations among probands.Molecular psychiatry · 2022Review
- Oxidative stress indices in ASD children in Sub-Sahara Africa.Journal of neurodevelopmental disorders · 2021Article
- Perturbed MAPK signaling in ASD: Impact of metal neurotoxicity.Current opinion in toxicology · 2021Article
- The Effect of Lead Exposure on Autism Development.International journal of molecular sciences · 2021Review
- Role of metallic pollutants in neurodegeneration: effects of aluminum, lead, mercury, and arsenic in mediating brain impairment events and autism spectrum disorder.Environmental science and pollution research international · 2021Review
- Environmental influence on neurodevelopmental disorders: Potential association of heavy metal exposure and autism.Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) · 2020Review
Corrections and comments
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Authors and funding
15 authors at 10 institutions in 1 country.
Funding
Abstract
Prenatal and perinatal exposures to air pollutants have been shown to adversely affect birth outcomes in offspring and may contribute to prevalence of autism spectrum disorder (ASD). For this ecologic study, we evaluated the association between ASD prevalence, at the census tract level, and proximity of tract centroids to the closest industrial facilities releasing arsenic, lead or mercury during the 1990s. We used 2000 to 2008 surveillance data from five sites of the Autism and Developmental Disabilities Monitoring (ADDM) network and 2000 census data to estimate prevalence. Multi-level negative binomial regression models were used to test associations between ASD prevalence and proximity to industrial facilities in existence from 1991 to 1999 according to the US Environmental Protection Agency Toxics Release Inventory (USEPA-TRI). Data for 2489 census tracts showed that after adjustment for demographic and socio-economic area-based characteristics, ASD prevalence was higher in census tracts located in the closest 10th percentile compared of distance to those in the furthest 50th percentile (adjusted RR=1.27, 95% CI: (1.00, 1.61), P=0.049). The findings observed in this study are suggestive of the association between urban residential proximity to industrial facilities emitting air pollutants and higher ASD prevalence.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.